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Anthropometric indicators of body composition in young adults: relation to size at birth and serial measurements of body mass index in childhood in the New Delhi birth cohort

Sachdev, Harshpal S., Fall, Caroline H.D., Osmond, Clive, Lakshmy, Ramakrishnan, Dey Biswas, Sushant K., Leary, Samantha D., Reddy, Kolli Srinath, Barker, David J.P. and Bhargava, Santosh K. (2005) Anthropometric indicators of body composition in young adults: relation to size at birth and serial measurements of body mass index in childhood in the New Delhi birth cohort American Journal of Clinical Nutrition, 82, (2), pp. 456-466.

Record type: Article

Abstract

Background: South Asians have a muscle-thin but adipose body phenotype and high rates of obesity-related disease. Adult body composition may be predictable in early life.
Objective: Anthropometric indexes of adult body composition were examined in relation to birth size and body mass index (BMI) during childhood.
Design: A population-based cohort of 1526 men and women aged 26–32 y in Delhi, India, who were measured sequentially from birth until 21 y of age were followed up. Adult weight, height, skinfold thicknesses, and waist and hip circumferences were measured. BMI and indexes of adiposity (sum of skinfold thicknesses), central adiposity (waist-hip ratio), and lean mass (residual values after adjustment of BMI for skinfold thicknesses and height) were derived.
Results: Mean birth weight was 2851 g. As children, many subjects were underweight-for-age (>2 SDs below the National Center for Health Statistics mean; 53% at 2 y), but as adults, 47% were overweight, 11% were obese, and 51% were centrally obese (according to World Health Organization criteria). Birth weight was positively related to adult lean mass (P < 0.001) and, in women only, to adiposity (P = 0.006) but was unrelated to central adiposity. BMI from birth to age 21 y was increasingly strongly positively correlated with all outcomes. BMI and BMI gain in infancy and early childhood were correlated more strongly with adult lean mass than with adiposity or central adiposity. Higher BMI and greater BMI gain in late childhood and adolescence were associated with increased adult adiposity and central adiposity.
Conclusions: Birth weight and BMI gain during infancy and early childhood predict adult lean mass more strongly than adult adiposity. Greater BMI gain in late childhood and adolescence predicts increased adult adiposity.

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More information

Published date: August 2005
Additional Information: Original research communication
Keywords: body composition, lean mass, obesity, developmental origins of adult disease, birth weight, childhood growth, nutritional transition, india

Identifiers

Local EPrints ID: 25967
URI: http://eprints.soton.ac.uk/id/eprint/25967
ISSN: 0002-9165
PURE UUID: 93362936-8147-4bb7-af7c-4289c779fca6
ORCID for Clive Osmond: ORCID iD orcid.org/0000-0002-9054-4655

Catalogue record

Date deposited: 21 Apr 2006
Last modified: 17 Jul 2017 16:08

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Contributors

Author: Harshpal S. Sachdev
Author: Clive Osmond ORCID iD
Author: Ramakrishnan Lakshmy
Author: Sushant K. Dey Biswas
Author: Samantha D. Leary
Author: Kolli Srinath Reddy
Author: David J.P. Barker
Author: Santosh K. Bhargava

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