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Cohort Profile: The Hertfordshire Cohort Study

Syddall, H.E., Aihie-Sayer, A., Dennison, E.M., Martin, H., Barker, D.J.P. and Cooper, C. (2005) Cohort Profile: The Hertfordshire Cohort Study International Journal of Epidemiology, 34, (6), pp. 1234-1242. (doi:10.1093/ije/dyi127).

Record type: Article


How did the study come about?
Ecological studies conducted in the 1980s demonstrated a close geographic correlation between death rates from coronary heart disease during the years 1968–78 in different parts of England and Wales and the infant mortality rate in these areas 60 years earlier.1 These studies suggested that adverse environmental influences acting in utero and during infancy might increase the risk of cardiovascular disease in later life. However, this hypothesis required investigation using more robust epidemiological techniques. To yield results within a relatively short space of time, a cohort study was needed which linked information about the early environment of individuals born at least 60 years earlier to their health outcomes in later life. As part of a nationwide search of archives, staff working at the MRC Environmental Epidemiology Unit (MRC EEU), University of Southampton, discovered a large set of records maintained in Hertfordshire during the early 20th century.

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Published date: 2005


Local EPrints ID: 26010
ISSN: 0300-5771
PURE UUID: 525d010d-aa10-4a28-a824-c621352b8c1e
ORCID for H.E. Syddall: ORCID iD
ORCID for C. Cooper: ORCID iD

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Date deposited: 21 Apr 2006
Last modified: 17 Jul 2017 16:08

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Author: H.E. Syddall ORCID iD
Author: A. Aihie-Sayer
Author: E.M. Dennison
Author: H. Martin
Author: D.J.P. Barker
Author: C. Cooper ORCID iD

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