Cohort Profile: The Hertfordshire Cohort Study
Cohort Profile: The Hertfordshire Cohort Study
How did the study come about?
Ecological studies conducted in the 1980s demonstrated a close geographic correlation between death rates from coronary heart disease during the years 1968–78 in different parts of England and Wales and the infant mortality rate in these areas 60 years earlier.1 These studies suggested that adverse environmental influences acting in utero and during infancy might increase the risk of cardiovascular disease in later life. However, this hypothesis required investigation using more robust epidemiological techniques. To yield results within a relatively short space of time, a cohort study was needed which linked information about the early environment of individuals born at least 60 years earlier to their health outcomes in later life. As part of a nationwide search of archives, staff working at the MRC Environmental Epidemiology Unit (MRC EEU), University of Southampton, discovered a large set of records maintained in Hertfordshire during the early 20th century.
1234-1242
Syddall, H.E.
a0181a93-8fc3-4998-a996-7963f0128328
Aihie-Sayer, A.
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Dennison, E.M.
ee647287-edb4-4392-8361-e59fd505b1d1
Martin, H.
c216843e-45cb-4fde-b2f5-dfdac4380cc7
Barker, D.J.P.
64c6005a-eea7-4c26-8f07-50d875998512
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
2005
Syddall, H.E.
a0181a93-8fc3-4998-a996-7963f0128328
Aihie-Sayer, A.
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Dennison, E.M.
ee647287-edb4-4392-8361-e59fd505b1d1
Martin, H.
c216843e-45cb-4fde-b2f5-dfdac4380cc7
Barker, D.J.P.
64c6005a-eea7-4c26-8f07-50d875998512
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Syddall, H.E., Aihie-Sayer, A., Dennison, E.M., Martin, H., Barker, D.J.P. and Cooper, C.
(2005)
Cohort Profile: The Hertfordshire Cohort Study.
International Journal of Epidemiology, 34 (6), .
(doi:10.1093/ije/dyi127).
Abstract
How did the study come about?
Ecological studies conducted in the 1980s demonstrated a close geographic correlation between death rates from coronary heart disease during the years 1968–78 in different parts of England and Wales and the infant mortality rate in these areas 60 years earlier.1 These studies suggested that adverse environmental influences acting in utero and during infancy might increase the risk of cardiovascular disease in later life. However, this hypothesis required investigation using more robust epidemiological techniques. To yield results within a relatively short space of time, a cohort study was needed which linked information about the early environment of individuals born at least 60 years earlier to their health outcomes in later life. As part of a nationwide search of archives, staff working at the MRC Environmental Epidemiology Unit (MRC EEU), University of Southampton, discovered a large set of records maintained in Hertfordshire during the early 20th century.
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More information
Published date: 2005
Identifiers
Local EPrints ID: 26010
URI: http://eprints.soton.ac.uk/id/eprint/26010
ISSN: 0300-5771
PURE UUID: 525d010d-aa10-4a28-a824-c621352b8c1e
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Date deposited: 21 Apr 2006
Last modified: 18 Mar 2024 02:48
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Contributors
Author:
A. Aihie-Sayer
Author:
H. Martin
Author:
D.J.P. Barker
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