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Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells

Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells
Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells
The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations.
human, embryonic germ cell, primordial germ cell, stem cell, embryo, gonad
1066-5099
212-220
Turnpenny, Lee W.
607f8dcf-ac66-4979-b63e-b77e0a13a186
Spalluto, Cosma M.
6802ad50-bc38-404f-9a19-40916425183b
Perrett, Rebecca M.
f69582f3-9fc6-497f-9a3e-2b93f972fd17
O'Shea, Marie
2d186adb-2d33-4951-b5a0-ed69f3f00113
Piper Hanley, Karen
f11a1076-ad7d-446e-bd59-96814475e06f
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
Wilson, David I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, Neil A.
bf03f7bb-f377-44fb-8344-0bb1ca8b2ef9
Turnpenny, Lee W.
607f8dcf-ac66-4979-b63e-b77e0a13a186
Spalluto, Cosma M.
6802ad50-bc38-404f-9a19-40916425183b
Perrett, Rebecca M.
f69582f3-9fc6-497f-9a3e-2b93f972fd17
O'Shea, Marie
2d186adb-2d33-4951-b5a0-ed69f3f00113
Piper Hanley, Karen
f11a1076-ad7d-446e-bd59-96814475e06f
Cameron, Iain T.
f7595539-efa6-4687-b161-e1e93ff710f2
Wilson, David I.
1500fca1-7082-4271-95f4-691f1d1252a2
Hanley, Neil A.
bf03f7bb-f377-44fb-8344-0bb1ca8b2ef9

Turnpenny, Lee W., Spalluto, Cosma M., Perrett, Rebecca M., O'Shea, Marie, Piper Hanley, Karen, Cameron, Iain T., Wilson, David I. and Hanley, Neil A. (2006) Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells. Stem Cells, 24 (2), 212-220. (doi:10.1634/stemcells.2005-0255).

Record type: Article

Abstract

The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations.

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More information

Published date: 2 February 2006
Additional Information: Embryonic Stem Cells-Characterization Series: concise review
Related URLs:
Keywords: human, embryonic germ cell, primordial germ cell, stem cell, embryo, gonad

Identifiers

Local EPrints ID: 26052
URI: http://eprints.soton.ac.uk/id/eprint/26052
DOI: doi:10.1634/stemcells.2005-0255
ISSN: 1066-5099
PURE UUID: a165cdc2-bdcd-4bd7-8301-79343471d5ed
ORCID for Cosma M. Spalluto: ORCID iD orcid.org/0000-0001-7273-0844
ORCID for Iain T. Cameron: ORCID iD orcid.org/0000-0002-4875-267X

Catalogue record

Date deposited: 12 Apr 2006
Last modified: 16 Mar 2024 03:24

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Contributors

Author: Lee W. Turnpenny
Author: Cosma M. Spalluto ORCID iD
Author: Rebecca M. Perrett
Author: Marie O'Shea
Author: Karen Piper Hanley
Author: Iain T. Cameron ORCID iD
Author: David I. Wilson
Author: Neil A. Hanley

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