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The prevention and treatment of glucocorticoid-induced osteoporosis in clinical practice

The prevention and treatment of glucocorticoid-induced osteoporosis in clinical practice
The prevention and treatment of glucocorticoid-induced osteoporosis in clinical practice
Glucocorticoids are associated with increased risk of bone loss and fracture. This study compared the prescribing of bone protective agents by rheumatologists in clinical practice with the standards recommended in the 1998 UK Consensus guidelines. All glucocorticoid users who attended rheumatology outpatients during a four-week period were eligible. Notes were audited according to a predefined proforma. Among the 1,290 rheumatology outpatients seen in the study period, 189 (15%) were taking glucocorticoids. 63% of glucocorticoid patients were taking calcium and 46% vitamin D. In total, 124 (71%) of the 175 patients available for review were at high risk of osteoporotic fracture, of whom 76 (61%) were taking appropriate prophylaxis. In 26 (15%) patients, insufficient information was available to be able to quantify the risk of fracture. The study showed that the audit standard was not met in 39% of cases. A better strategy for the monitoring of clinical risk factors is therefore required.
glucocorticoid-induced osteoporosis, guidelines, prophylaxis
1470-2118
431-436
Walker-Bone, Karen
ad7d1336-ed2c-4f39-ade5-da84eb412109
Wood, Angela
797aaf86-157c-4cb6-89c6-e095928e6ba7
Hull, Richard
1c448d24-9c0e-4054-919c-74359171f5a5
Ledingham, Joanna
0cd83c39-90a3-4ca7-88b0-dad74e5bbc7c
McCrae, Fiona C.
138c8ea9-0806-4b75-8cd7-f33caba22ceb
Shaban, Ragai
d4aa757d-1475-45ad-8e63-0bec89168840
Thomas, Alastair
c025c595-bcb6-4f23-b3da-22a7ae48fd35
Mackay, Kirsten
005e75da-525e-4e35-b245-b285821e6abe
Walker-Bone, Karen
ad7d1336-ed2c-4f39-ade5-da84eb412109
Wood, Angela
797aaf86-157c-4cb6-89c6-e095928e6ba7
Hull, Richard
1c448d24-9c0e-4054-919c-74359171f5a5
Ledingham, Joanna
0cd83c39-90a3-4ca7-88b0-dad74e5bbc7c
McCrae, Fiona C.
138c8ea9-0806-4b75-8cd7-f33caba22ceb
Shaban, Ragai
d4aa757d-1475-45ad-8e63-0bec89168840
Thomas, Alastair
c025c595-bcb6-4f23-b3da-22a7ae48fd35
Mackay, Kirsten
005e75da-525e-4e35-b245-b285821e6abe

Walker-Bone, Karen, Wood, Angela, Hull, Richard, Ledingham, Joanna, McCrae, Fiona C., Shaban, Ragai, Thomas, Alastair and Mackay, Kirsten (2004) The prevention and treatment of glucocorticoid-induced osteoporosis in clinical practice. Clinical Medicine, 4 (5), 431-436.

Record type: Article

Abstract

Glucocorticoids are associated with increased risk of bone loss and fracture. This study compared the prescribing of bone protective agents by rheumatologists in clinical practice with the standards recommended in the 1998 UK Consensus guidelines. All glucocorticoid users who attended rheumatology outpatients during a four-week period were eligible. Notes were audited according to a predefined proforma. Among the 1,290 rheumatology outpatients seen in the study period, 189 (15%) were taking glucocorticoids. 63% of glucocorticoid patients were taking calcium and 46% vitamin D. In total, 124 (71%) of the 175 patients available for review were at high risk of osteoporotic fracture, of whom 76 (61%) were taking appropriate prophylaxis. In 26 (15%) patients, insufficient information was available to be able to quantify the risk of fracture. The study showed that the audit standard was not met in 39% of cases. A better strategy for the monitoring of clinical risk factors is therefore required.

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More information

Published date: 2004
Keywords: glucocorticoid-induced osteoporosis, guidelines, prophylaxis

Identifiers

Local EPrints ID: 26101
URI: http://eprints.soton.ac.uk/id/eprint/26101
ISSN: 1470-2118
PURE UUID: b7948085-5c80-488d-93ad-5f0384ad72e4
ORCID for Karen Walker-Bone: ORCID iD orcid.org/0000-0002-5992-1459

Catalogue record

Date deposited: 12 Apr 2006
Last modified: 08 Jan 2022 02:51

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Contributors

Author: Angela Wood
Author: Richard Hull
Author: Joanna Ledingham
Author: Fiona C. McCrae
Author: Ragai Shaban
Author: Alastair Thomas
Author: Kirsten Mackay

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