Multidimensional Epistasis and the Advantage of Sex
Multidimensional Epistasis and the Advantage of Sex
Kondrashov and Kondrashov (2001) suggest that there is usually a disadvantage for sex in systems with multidimensional epistasis. They define systems of 'unidimensional epistasis' to be those where the fitness of a genotype is a function of the number of mutations it carries, and in contrast describe a system where the fitness of a genotype is a function of the numbers of mutations in two (or more) disjoint subsets of loci creating 'multidimensional epistasis'. In an example landscape an asexual population evolves fit genotypes about twice as fast as a sexual one. Here we examine other landscapes with multidimensional epistasis and find cases where an asexual population evolves fit genotypes 20 and 180 times slower than a sexual population.
2792-2799
Watson, Richard A.
ce199dfc-d5d4-4edf-bd7b-f9e224c96c75
Wakeley, John
a56e0da3-ddcc-4cdc-9d54-e652231160e5
2005
Watson, Richard A.
ce199dfc-d5d4-4edf-bd7b-f9e224c96c75
Wakeley, John
a56e0da3-ddcc-4cdc-9d54-e652231160e5
Watson, Richard A. and Wakeley, John
(2005)
Multidimensional Epistasis and the Advantage of Sex.
In 2005 IEEE Congress on Evolutionary Computation.
vol. 3,
IEEE.
.
Record type:
Conference or Workshop Item
(Paper)
Abstract
Kondrashov and Kondrashov (2001) suggest that there is usually a disadvantage for sex in systems with multidimensional epistasis. They define systems of 'unidimensional epistasis' to be those where the fitness of a genotype is a function of the number of mutations it carries, and in contrast describe a system where the fitness of a genotype is a function of the numbers of mutations in two (or more) disjoint subsets of loci creating 'multidimensional epistasis'. In an example landscape an asexual population evolves fit genotypes about twice as fast as a sexual one. Here we examine other landscapes with multidimensional epistasis and find cases where an asexual population evolves fit genotypes 20 and 180 times slower than a sexual population.
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cec2005_306watson_mdeas.pdf
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Published date: 2005
Organisations:
Agents, Interactions & Complexity
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Local EPrints ID: 261611
URI: http://eprints.soton.ac.uk/id/eprint/261611
PURE UUID: 5e31b414-97a5-4606-97d1-9031b65ead0a
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Date deposited: 30 Nov 2005
Last modified: 16 Mar 2024 03:42
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Author:
Richard A. Watson
Author:
John Wakeley
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