The University of Southampton
University of Southampton Institutional Repository

Synaptic and Temporal Ensemble Interpretation of Spike Timing Dependent Plasticity

Synaptic and Temporal Ensemble Interpretation of Spike Timing Dependent Plasticity
Synaptic and Temporal Ensemble Interpretation of Spike Timing Dependent Plasticity
We postulate that a simple, three-state synaptic switch governs changes in synaptic strength at individual synapses. Under this switch rule, we show that a variety of experimental results on timing-dependent plasticity can emerge from temporal and spatial averaging over multiple synapses and multiple spike pairings. In particular, we show that a critical window for the interaction of pre- and postsynaptic spikes emerges as an ensemble property of the collective system, with individual synapses exhibiting only a minimal form of spike coincidence detection. In addition, we show that a Bienenstock-Cooper-Munro-like, rate-based plasticity rule emerges directly from such a model. This demonstrates that two, apparently separate, forms of neuronal plasticity can emerge from a much simpler rule governing the plasticity of individual synapses.
2316-2336
Appleby, Peter
98b8b676-f0a6-4451-ab48-c0358730b529
Elliott, Terry
b4262f0d-c295-4ea4-b5d8-3931470952f9
Appleby, Peter
98b8b676-f0a6-4451-ab48-c0358730b529
Elliott, Terry
b4262f0d-c295-4ea4-b5d8-3931470952f9

Appleby, Peter and Elliott, Terry (2005) Synaptic and Temporal Ensemble Interpretation of Spike Timing Dependent Plasticity. Neural Computation, 2005, 2316-2336.

Record type: Article

Abstract

We postulate that a simple, three-state synaptic switch governs changes in synaptic strength at individual synapses. Under this switch rule, we show that a variety of experimental results on timing-dependent plasticity can emerge from temporal and spatial averaging over multiple synapses and multiple spike pairings. In particular, we show that a critical window for the interaction of pre- and postsynaptic spikes emerges as an ensemble property of the collective system, with individual synapses exhibiting only a minimal form of spike coincidence detection. In addition, we show that a Bienenstock-Cooper-Munro-like, rate-based plasticity rule emerges directly from such a model. This demonstrates that two, apparently separate, forms of neuronal plasticity can emerge from a much simpler rule governing the plasticity of individual synapses.

Text
p2316.pdf - Other
Restricted to Registered users only
Download (179kB)
Request a copy

More information

Published date: 2005
Organisations: Web & Internet Science

Identifiers

Local EPrints ID: 262115
URI: http://eprints.soton.ac.uk/id/eprint/262115
PURE UUID: ab3667ec-b3ea-483e-a052-817d541d1aa0

Catalogue record

Date deposited: 23 Mar 2006
Last modified: 14 Mar 2024 07:05

Export record

Contributors

Author: Peter Appleby
Author: Terry Elliott

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×