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Hypercalcaemia, parathyroid hormone-related protein and malignancy

Record type: Article

Hypercalcaemia is the most common serious metabolic complication of malignancy. Recent advances have significantly increased our understanding of the pathophysiology of hypercalcaemia of malignancy and revealed the importance of parathyroid hormone-related protein (PTHrP) in a wide range of physiological and pathological processes. This review examines the pathophysiology of hypercalcaemia of malignancy, focusing on the role of PTHrP before discussing further pathological and physiological processes in which PTHrP may be implicated, and the impact of this knowledge on the management of malignant disease.

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Citation

Bayne, M.C. and Illidge, T.M. (2001) Hypercalcaemia, parathyroid hormone-related protein and malignancy Clinical Oncology, 13, (5), pp. 372-377. (doi:10.1053/clon.2001.9293).

More information

Published date: 2001
Keywords: bisphosphonates, bone metastasis, hypercalcaemia, parathyroid hormone-related protein

Identifiers

Local EPrints ID: 26217
URI: http://eprints.soton.ac.uk/id/eprint/26217
ISSN: 0936-6555
PURE UUID: 00faab10-14d4-4de5-9449-3eb07135dc25

Catalogue record

Date deposited: 24 Apr 2006
Last modified: 17 Jul 2017 16:08

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Contributors

Author: M.C. Bayne
Author: T.M. Illidge

University divisions


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