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Hypercalcaemia, parathyroid hormone-related protein and malignancy

Bayne, M.C. and Illidge, T.M. (2001) Hypercalcaemia, parathyroid hormone-related protein and malignancy Clinical Oncology, 13, (5), pp. 372-377. (doi:10.1053/clon.2001.9293).

Record type: Article


Hypercalcaemia is the most common serious metabolic complication of malignancy. Recent advances have significantly increased our understanding of the pathophysiology of hypercalcaemia of malignancy and revealed the importance of parathyroid hormone-related protein (PTHrP) in a wide range of physiological and pathological processes. This review examines the pathophysiology of hypercalcaemia of malignancy, focusing on the role of PTHrP before discussing further pathological and physiological processes in which PTHrP may be implicated, and the impact of this knowledge on the management of malignant disease.

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Published date: 2001
Keywords: bisphosphonates, bone metastasis, hypercalcaemia, parathyroid hormone-related protein


Local EPrints ID: 26217
ISSN: 0936-6555
PURE UUID: 00faab10-14d4-4de5-9449-3eb07135dc25

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Date deposited: 24 Apr 2006
Last modified: 17 Jul 2017 16:08

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Author: M.C. Bayne
Author: T.M. Illidge

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