Hypercalcaemia, parathyroid hormone-related protein and malignancy


Bayne, M.C. and Illidge, T.M. (2001) Hypercalcaemia, parathyroid hormone-related protein and malignancy Clinical Oncology, 13, (5), pp. 372-377. (doi:10.1053/clon.2001.9293).

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Description/Abstract

Hypercalcaemia is the most common serious metabolic complication of malignancy. Recent advances have significantly increased our understanding of the pathophysiology of hypercalcaemia of malignancy and revealed the importance of parathyroid hormone-related protein (PTHrP) in a wide range of physiological and pathological processes. This review examines the pathophysiology of hypercalcaemia of malignancy, focusing on the role of PTHrP before discussing further pathological and physiological processes in which PTHrP may be implicated, and the impact of this knowledge on the management of malignant disease.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1053/clon.2001.9293
ISSNs: 0936-6555 (print)
Related URLs:
Keywords: bisphosphonates, bone metastasis, hypercalcaemia, parathyroid hormone-related protein
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ePrint ID: 26217
Date :
Date Event
2001Published
Date Deposited: 24 Apr 2006
Last Modified: 16 Apr 2017 22:34
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/26217

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