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3D focusing of nanoparticles in microfluidic channels

3D focusing of nanoparticles in microfluidic channels
3D focusing of nanoparticles in microfluidic channels
Dynamic focusing of particles can be used to centre particles in a fluid stream, ensuring the passage of the particles through a specified detection volume. This paper describes a method for focusing nanoparticles using dielectrophoresis. The method differs from other focusing methods in that it manipulates the particles and not the fluid. Experimental focusing is demonstrated for a range of different particle types, and discussed in terms of the operational limits of the device. Dynamic numerical simulations of the particle motion in the device are presented and compared with the experimental results. The potential of the device for nanoparticle control and manipulation in microfluidic chips is discussed.
76-81
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Holmes, David
eeff86f7-ab4b-4795-9a01-82ce1275e34f
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Holmes, David
eeff86f7-ab4b-4795-9a01-82ce1275e34f
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581

Morgan, Hywel, Holmes, David and Green, Nicolas G (2003) 3D focusing of nanoparticles in microfluidic channels. IEE Proceedings - Nanobiotechnology, 150 (2), 76-81. (doi:10.1049/ip-nbt:20031090).

Record type: Article

Abstract

Dynamic focusing of particles can be used to centre particles in a fluid stream, ensuring the passage of the particles through a specified detection volume. This paper describes a method for focusing nanoparticles using dielectrophoresis. The method differs from other focusing methods in that it manipulates the particles and not the fluid. Experimental focusing is demonstrated for a range of different particle types, and discussed in terms of the operational limits of the device. Dynamic numerical simulations of the particle motion in the device are presented and compared with the experimental results. The potential of the device for nanoparticle control and manipulation in microfluidic chips is discussed.

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More information

Published date: 2003
Organisations: Electronics & Computer Science

Identifiers

Local EPrints ID: 262680
URI: https://eprints.soton.ac.uk/id/eprint/262680
PURE UUID: d07e8062-8152-438c-bf20-e362705464ec
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676
ORCID for Nicolas G Green: ORCID iD orcid.org/0000-0001-9230-4455

Catalogue record

Date deposited: 07 Jun 2006
Last modified: 10 Sep 2019 00:45

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Contributors

Author: Hywel Morgan ORCID iD
Author: David Holmes
Author: Nicolas G Green ORCID iD

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