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Variability of quantitative polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicenter study

Variability of quantitative polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicenter study
Variability of quantitative polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicenter study
The t(14;18)(q32;q21) chromosomal translocation is closely associated with follicular lymphoma. Polymerase chain reaction (PCR) analysis has high sensitivity and is used to assess responses to therapy. Quantification of translocation-bearing cells is a possible advantage of real-time PCR over conventional PCR. A collaborative study comparing results from 12 international laboratories is reported.
0390-6078
1706-1707
Darby, A.J.
2f468f4f-7eff-45b9-abbe-89feef3e7575
Lanham, S.
366f5da6-cf09-4a87-9ecd-0b08a902f7ec
Soubeyran, P.
14f8fc45-1a28-4841-835e-e6131661f16c
Johnson, P.W.
e01f93bd-4ce9-473a-991c-b770f4a6029b
Darby, A.J.
2f468f4f-7eff-45b9-abbe-89feef3e7575
Lanham, S.
366f5da6-cf09-4a87-9ecd-0b08a902f7ec
Soubeyran, P.
14f8fc45-1a28-4841-835e-e6131661f16c
Johnson, P.W.
e01f93bd-4ce9-473a-991c-b770f4a6029b

Darby, A.J., Lanham, S., Soubeyran, P. and Johnson, P.W. (2005) Variability of quantitative polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicenter study. Haematologica, 90 (12), 1706-1707.

Record type: Article

Abstract

The t(14;18)(q32;q21) chromosomal translocation is closely associated with follicular lymphoma. Polymerase chain reaction (PCR) analysis has high sensitivity and is used to assess responses to therapy. Quantification of translocation-bearing cells is a possible advantage of real-time PCR over conventional PCR. A collaborative study comparing results from 12 international laboratories is reported.

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Published date: 2005
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Local EPrints ID: 26274
URI: http://eprints.soton.ac.uk/id/eprint/26274
ISSN: 0390-6078
PURE UUID: 9ee03761-c5bd-43f3-bb90-4c4d5492ac63

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Date deposited: 20 Apr 2006
Last modified: 22 Jul 2022 20:33

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Contributors

Author: A.J. Darby
Author: S. Lanham
Author: P. Soubeyran
Author: P.W. Johnson

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