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Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics

Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics
Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics
A variable proportion of cancers have a genetic aetiology but genes rarely act alone in shaping cancer predisposition. Environment and other genes modify risks and much of this interaction is poorly understood at present. Initial genetic risk assessment is often based on knowledge of genetic epidemiology. Different levels of increase in predicted risk may shape clinical decisions about molecular genetic testing, prevention or early detection, and knowledge about available options is important in dealing with cancer patients and their families.
0923-7534
iv133-iv138
Eccles, D.M.
5b59bc73-11c9-4cf0-a9d5-7a8e523eee23
Eccles, D.M.
5b59bc73-11c9-4cf0-a9d5-7a8e523eee23

Eccles, D.M. (2004) Hereditary cancer: guidelines in clinical practice. Breast and ovarian cancer genetics. Annals of Oncology, 15 (4), iv133-iv138. (doi:10.1093/annonc/mdh917).

Record type: Article

Abstract

A variable proportion of cancers have a genetic aetiology but genes rarely act alone in shaping cancer predisposition. Environment and other genes modify risks and much of this interaction is poorly understood at present. Initial genetic risk assessment is often based on knowledge of genetic epidemiology. Different levels of increase in predicted risk may shape clinical decisions about molecular genetic testing, prevention or early detection, and knowledge about available options is important in dealing with cancer patients and their families.

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More information

Published date: 2004
Organisations: Cancer Sciences

Identifiers

Local EPrints ID: 26287
URI: http://eprints.soton.ac.uk/id/eprint/26287
ISSN: 0923-7534
PURE UUID: 9f5f41d4-d437-4621-ac4e-5a07fab7d693
ORCID for D.M. Eccles: ORCID iD orcid.org/0000-0002-9935-3169

Catalogue record

Date deposited: 21 Apr 2006
Last modified: 16 Mar 2024 02:39

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