Acoustic Particle Manipulation to Enhance the Sensing of Cells within Microfluidic Chambers
Acoustic Particle Manipulation to Enhance the Sensing of Cells within Microfluidic Chambers
The sensing of cells within micro-fluidic components can be greatly enhanced by maximizing the concentration of particles around the sensor element. To encourage bacterial cells to move to a surface, acoustic radiation forces are employed, which rely on the compressibility and density of the particulate matter. This provides an alternative to electric or magnetic field-assisted particle manipulation, and can operate over greater length scales. This paper describes the simulation of a device used to demonstrate the principle and reveals how the geometric design of the system influences the acoustic field and is paramount to the particle manipulation process. Predictions of particle concentrations upon a surface compare excellently with experimental results
193-196
Townsend, R
23b8f68c-d775-41a9-90b1-108382b50650
Hill, M
13d08973-687e-423b-9a2c-392dd6848548
Harris, NR
237cfdbd-86e4-4025-869c-c85136f14dfd
Stacey, SP
4d97c0c9-b4b3-4720-9e56-201738dac6d4
Kuznetsova, LA
bb0f0e0d-17fb-4d78-8462-048ad791ec50
Borthwick, KAJ
a425f938-e4eb-41dc-81a8-ee4948b68c9b
Coakley, WT
0f8cd856-148d-4c18-999d-6d40672ca800
2006
Townsend, R
23b8f68c-d775-41a9-90b1-108382b50650
Hill, M
13d08973-687e-423b-9a2c-392dd6848548
Harris, NR
237cfdbd-86e4-4025-869c-c85136f14dfd
Stacey, SP
4d97c0c9-b4b3-4720-9e56-201738dac6d4
Kuznetsova, LA
bb0f0e0d-17fb-4d78-8462-048ad791ec50
Borthwick, KAJ
a425f938-e4eb-41dc-81a8-ee4948b68c9b
Coakley, WT
0f8cd856-148d-4c18-999d-6d40672ca800
Townsend, R, Hill, M, Harris, NR, Stacey, SP, Kuznetsova, LA, Borthwick, KAJ and Coakley, WT
(2006)
Acoustic Particle Manipulation to Enhance the Sensing of Cells within Microfluidic Chambers.
17th MicroMechanics Europe, Southampton.
03 - 05 Sep 2006.
.
Record type:
Conference or Workshop Item
(Poster)
Abstract
The sensing of cells within micro-fluidic components can be greatly enhanced by maximizing the concentration of particles around the sensor element. To encourage bacterial cells to move to a surface, acoustic radiation forces are employed, which rely on the compressibility and density of the particulate matter. This provides an alternative to electric or magnetic field-assisted particle manipulation, and can operate over greater length scales. This paper describes the simulation of a device used to demonstrate the principle and reveals how the geometric design of the system influences the acoustic field and is paramount to the particle manipulation process. Predictions of particle concentrations upon a surface compare excellently with experimental results
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MME06_Townsend.doc
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Poster_MME.ppt
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Published date: 2006
Additional Information:
Event Dates: 3-5 September 2006
Venue - Dates:
17th MicroMechanics Europe, Southampton, 2006-09-03 - 2006-09-05
Organisations:
EEE
Identifiers
Local EPrints ID: 263153
URI: http://eprints.soton.ac.uk/id/eprint/263153
PURE UUID: 799bde1d-c8d3-467d-ae3a-e3ac35aad9cd
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Date deposited: 21 Dec 2006
Last modified: 07 Dec 2024 02:34
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Contributors
Author:
R Townsend
Author:
M Hill
Author:
NR Harris
Author:
SP Stacey
Author:
LA Kuznetsova
Author:
KAJ Borthwick
Author:
WT Coakley
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