Single-cell impedance spectroscopy: maximum length sequence analysis
Single-cell impedance spectroscopy: maximum length sequence analysis
A novel broadband high-speed impedance spectrometer has been developed for the analysis of single biological particles in a high-throughput microfluidic cytometer. The technique is based on obtaining the impulse response of the system using maximum length sequences (MLS) as the excitation signal. The impulse response is converted into the frequency domain using Fast Fourier Transform (FFT). Theoretical modeling and simulation of a single cell suspended in the cytometer show that the MLS technique is capable of high precision single particle analysis.
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Gawad, Shady
98f746a7-4bcc-42bb-a450-dafda85be29c
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
2007
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Gawad, Shady
98f746a7-4bcc-42bb-a450-dafda85be29c
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Sun, Tao, Green, Nicolas G, Gawad, Shady and Morgan, Hywel
(2007)
Single-cell impedance spectroscopy: maximum length sequence analysis.
SPIE, Smart Materials, Nano- & Micro-Smart Systems, Adelaide, Australia.
10 - 13 Dec 2006.
Record type:
Conference or Workshop Item
(Paper)
Abstract
A novel broadband high-speed impedance spectrometer has been developed for the analysis of single biological particles in a high-throughput microfluidic cytometer. The technique is based on obtaining the impulse response of the system using maximum length sequences (MLS) as the excitation signal. The impulse response is converted into the frequency domain using Fast Fourier Transform (FFT). Theoretical modeling and simulation of a single cell suspended in the cytometer show that the MLS technique is capable of high precision single particle analysis.
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Published date: 2007
Additional Information:
Event Dates: 10 - 13 December 2006
Venue - Dates:
SPIE, Smart Materials, Nano- & Micro-Smart Systems, Adelaide, Australia, 2006-12-10 - 2006-12-13
Organisations:
Nanoelectronics and Nanotechnology
Identifiers
Local EPrints ID: 263385
URI: http://eprints.soton.ac.uk/id/eprint/263385
PURE UUID: 4c26a675-f719-414d-95d8-587fb1963201
Catalogue record
Date deposited: 06 Feb 2007
Last modified: 08 Jan 2022 03:00
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Contributors
Author:
Tao Sun
Author:
Nicolas G Green
Author:
Shady Gawad
Author:
Hywel Morgan
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