Electroporation – how different length and shaped electrical pulses affect the permeability of cells
Electroporation – how different length and shaped electrical pulses affect the permeability of cells
Studies into electroporation have grown increasingly popular over the past few years; many studies have been presented both theoretically and practically based. Now presented is a numerical simulation study of the applied pulse amplitude, duration and shape and how these factors relate to the number of pores created during this process. Pulse shapes studied include rectangular, exponential and triangular pulses. Results suggest that out of the most common pulse shapes rectangular pulses are the most efficient pore producers, these results agree with prior studies however disagree with one study, which uses the same model for simulation.
electroporation, biological cell, electric pulse, numerical simulation
1-4244-0547-5
353-356
Daly, K.
f40a9985-ef81-4d7e-a7ea-defa8cf8a533
Chen, G.
3de45a9c-6c9a-4bcb-90c3-d7e26be21819
2006
Daly, K.
f40a9985-ef81-4d7e-a7ea-defa8cf8a533
Chen, G.
3de45a9c-6c9a-4bcb-90c3-d7e26be21819
Daly, K. and Chen, G.
(2006)
Electroporation – how different length and shaped electrical pulses affect the permeability of cells.
2006 Annual Report on Conference on Electrical Insulation and Dielectric Phenomena, Kansas City, United States.
15 - 18 Oct 2006.
.
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Conference or Workshop Item
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Abstract
Studies into electroporation have grown increasingly popular over the past few years; many studies have been presented both theoretically and practically based. Now presented is a numerical simulation study of the applied pulse amplitude, duration and shape and how these factors relate to the number of pores created during this process. Pulse shapes studied include rectangular, exponential and triangular pulses. Results suggest that out of the most common pulse shapes rectangular pulses are the most efficient pore producers, these results agree with prior studies however disagree with one study, which uses the same model for simulation.
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Published date: 2006
Venue - Dates:
2006 Annual Report on Conference on Electrical Insulation and Dielectric Phenomena, Kansas City, United States, 2006-10-15 - 2006-10-18
Keywords:
electroporation, biological cell, electric pulse, numerical simulation
Organisations:
EEE
Identifiers
Local EPrints ID: 263478
URI: http://eprints.soton.ac.uk/id/eprint/263478
ISBN: 1-4244-0547-5
PURE UUID: 4df1785d-a039-4d27-a5d1-071971691c28
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Date deposited: 18 Feb 2007
Last modified: 14 Mar 2024 07:32
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Contributors
Author:
K. Daly
Author:
G. Chen
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