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Impedance spectroscopy using maximum length sequences: Application to single cell analysis

Impedance spectroscopy using maximum length sequences: Application to single cell analysis
Impedance spectroscopy using maximum length sequences: Application to single cell analysis
A maximum length sequence MLS is used to perform broadband impedance spectroscopy on a dielectric sample. The method has a number of advantages over other pulse-based or frequency sweep techniques. It requires the application of a very short sequence of voltage steps in the microsecond range and therefore allows the measurement of time-dependent impedance of a sample with high temporal resolution over a large bandwidth. The technique is demonstrated using a time-invariant passive RC network. The impedance of single biological cell flowing in a microfluidic channel is also measured, showing that MLS is an ideal method for high speed impedance analysis.
0034-6748
54301
Gawad, Shady
98f746a7-4bcc-42bb-a450-dafda85be29c
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Gawad, Shady
98f746a7-4bcc-42bb-a450-dafda85be29c
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Green, Nicolas G
d9b47269-c426-41fd-a41d-5f4579faa581
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174

Gawad, Shady, Sun, Tao, Green, Nicolas G and Morgan, Hywel (2007) Impedance spectroscopy using maximum length sequences: Application to single cell analysis. Review of Scientific Instruments, 78, 54301. (doi:10.1063/1.2737751).

Record type: Article

Abstract

A maximum length sequence MLS is used to perform broadband impedance spectroscopy on a dielectric sample. The method has a number of advantages over other pulse-based or frequency sweep techniques. It requires the application of a very short sequence of voltage steps in the microsecond range and therefore allows the measurement of time-dependent impedance of a sample with high temporal resolution over a large bandwidth. The technique is demonstrated using a time-invariant passive RC network. The impedance of single biological cell flowing in a microfluidic channel is also measured, showing that MLS is an ideal method for high speed impedance analysis.

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J37_Gawad_Sun_Green_Morgan_Review_of_Scientific_Instruments_2007.pdf - Other
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Published date: 2007
Organisations: Electronics & Computer Science

Identifiers

Local EPrints ID: 264101
URI: http://eprints.soton.ac.uk/id/eprint/264101
ISSN: 0034-6748
PURE UUID: bca7fda5-3b47-4261-8c8a-8fcbce6edf6c
ORCID for Nicolas G Green: ORCID iD orcid.org/0000-0001-9230-4455
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676

Catalogue record

Date deposited: 30 May 2007
Last modified: 15 Mar 2024 03:20

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Contributors

Author: Shady Gawad
Author: Tao Sun
Author: Nicolas G Green ORCID iD
Author: Hywel Morgan ORCID iD

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