The University of Southampton
University of Southampton Institutional Repository

Air-Exposure Technique for the Formation of Artificial Lipid Bilayers in Microsystems

Sandison, M.E., Zagnoni, M. and Morgan, H. (2007) Air-Exposure Technique for the Formation of Artificial Lipid Bilayers in Microsystems Langmuir, 23, pp. 8277-8284.

Record type: Article


To develop a reliable method for on-chip bilayer lipid membrane (BLM) formation, which could be employed for use in a biosensor array platform, a polymer microfluidic device has been constructed, and the formation of suspended BLMs within it has been investigated. A simple, yet reproducible BLM formation protocol has been developed, in which a brief air-exposure period is employed to induce the rapid thinning of an initially thick lipid-solvent layer. The technique is rapid, reproducible, and amenable to the simple injection of proteins or analytes, as well as to buffer exchange on both sides of the membrane. Scaling up the technique for use in an array platform is also straightforward, the simultaneous formation of three individually addressable BLMs being demonstrated.

Full text not available from this repository.

More information

Published date: 2007
Organisations: Nanoelectronics and Nanotechnology


Local EPrints ID: 264502
ISSN: 0743-7463
PURE UUID: e7abe148-eff2-4e1e-ac12-471fbb5ef5fa
ORCID for H. Morgan: ORCID iD

Catalogue record

Date deposited: 14 Sep 2007
Last modified: 18 Jul 2017 07:34

Export record


Author: M.E. Sandison
Author: M. Zagnoni
Author: H. Morgan ORCID iD

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.