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Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers

Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers
Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers
A polymer microfluidic device has been fabricated using rapid prototyping techniques. The device was built up to allow the formation and subsequent investigatyion of artificial bilayer lipid membranes (BLMs). A simple dry film photoresist stamp was used to hot emboss microfluidic channels into PMMA films. Laser micromachining was employed to form an aperture into PMMA films. Laser micromachining was employed to form an aperture through the PMMA channels, across which the BLM was later formed. The dry film phororesist was also used as a simple etch mask for the deep etching of glass substrates in buffered HF solutions, which was used in this work for the production of glass embossing stamps. We show that bilayer films can be successfully produced across laser micromachined apertures in PMMA films.
0960-1317
S139-S144
Sandison, M E
18641143-283c-4a25-a4d1-a46453b7178e
Morgan, H
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Sandison, M E
18641143-283c-4a25-a4d1-a46453b7178e
Morgan, H
de00d59f-a5a2-48c4-a99a-1d5dd7854174

Sandison, M E and Morgan, H (2005) Rapid fabrication of polymer microfluidic systems for the production of artificial lipid bilayers. Journal of Micromechanics and Microengineering, 15, S139-S144.

Record type: Article

Abstract

A polymer microfluidic device has been fabricated using rapid prototyping techniques. The device was built up to allow the formation and subsequent investigatyion of artificial bilayer lipid membranes (BLMs). A simple dry film photoresist stamp was used to hot emboss microfluidic channels into PMMA films. Laser micromachining was employed to form an aperture into PMMA films. Laser micromachining was employed to form an aperture through the PMMA channels, across which the BLM was later formed. The dry film phororesist was also used as a simple etch mask for the deep etching of glass substrates in buffered HF solutions, which was used in this work for the production of glass embossing stamps. We show that bilayer films can be successfully produced across laser micromachined apertures in PMMA films.

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More information

Published date: June 2005
Organisations: Nanoelectronics and Nanotechnology

Identifiers

Local EPrints ID: 264530
URI: https://eprints.soton.ac.uk/id/eprint/264530
ISSN: 0960-1317
PURE UUID: 67c89e74-54c7-47e4-974a-cb7f090d0c44
ORCID for H Morgan: ORCID iD orcid.org/0000-0003-4850-5676

Catalogue record

Date deposited: 19 Sep 2007
Last modified: 19 Jul 2019 00:57

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