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Superimposed Nanostructured Diffraction Gratings as High Capacity Barcodes for Biological and Chemical Applications

Superimposed Nanostructured Diffraction Gratings as High Capacity Barcodes for Biological and Chemical Applications
Superimposed Nanostructured Diffraction Gratings as High Capacity Barcodes for Biological and Chemical Applications

We describe a new non-contact high capacity optical tagging technique for bead based assays, based on the use of nanostructured barcodes. The tags are generated from a number of superimposed diffraction gratings. With one-dimensional diffraction, capacity for up to 68,000 distinguishable tags has been demonstrated, with a theoretical capacity of up to 109 tags. Extension into two dimensions increases this theoretical limit to 1021 tags.
diffraction gratings, optical barcodes, biological applications, combinatorial chemistry
0030-4018
1789-1795
Birtwell, S.W.
8dca4d3a-2c9e-415c-b9c2-6b3a07bbf5c4
Galitonov, G.S.
c1bff27b-c0f3-43b1-b131-a5a3f4164b59
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Zheludev, N.I.
32fb6af7-97e4-4d11-bca6-805745e40cc6
Birtwell, S.W.
8dca4d3a-2c9e-415c-b9c2-6b3a07bbf5c4
Galitonov, G.S.
c1bff27b-c0f3-43b1-b131-a5a3f4164b59
Morgan, H.
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Zheludev, N.I.
32fb6af7-97e4-4d11-bca6-805745e40cc6

Birtwell, S.W., Galitonov, G.S., Morgan, H. and Zheludev, N.I. (2008) Superimposed Nanostructured Diffraction Gratings as High Capacity Barcodes for Biological and Chemical Applications. Optics Communications, 281 (7), 1789-1795. (doi:10.1016/j.optcom.2007.04.066).

Record type: Article

Abstract


We describe a new non-contact high capacity optical tagging technique for bead based assays, based on the use of nanostructured barcodes. The tags are generated from a number of superimposed diffraction gratings. With one-dimensional diffraction, capacity for up to 68,000 distinguishable tags has been demonstrated, with a theoretical capacity of up to 109 tags. Extension into two dimensions increases this theoretical limit to 1021 tags.

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Published date: April 2008
Keywords: diffraction gratings, optical barcodes, biological applications, combinatorial chemistry
Organisations: Optoelectronics Research Centre

Identifiers

Local EPrints ID: 266506
URI: http://eprints.soton.ac.uk/id/eprint/266506
ISSN: 0030-4018
PURE UUID: 646cc368-e298-48a2-b753-c67103df1f4e
ORCID for H. Morgan: ORCID iD orcid.org/0000-0003-4850-5676
ORCID for N.I. Zheludev: ORCID iD orcid.org/0000-0002-1013-6636

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Date deposited: 04 Aug 2008 03:57
Last modified: 15 Mar 2024 03:18

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Contributors

Author: S.W. Birtwell
Author: G.S. Galitonov
Author: H. Morgan ORCID iD
Author: N.I. Zheludev ORCID iD

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