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Development of an EORTC disease-specific quality of life module for use in patients with gastric cancer

Record type: Article

Quality of life (QL) is an important outcome in clinical trials in oncology. There is currently no valid international QL measure for gastric cancer. This paper describes the development of a QL module for gastric cancer to supplement the European Organization for Research and Treatment of Cancer (EORTC) Quality of life (QLQ-C30) questionnaire. Phases I to III of module development were conducted in the United Kingdom, France, Germany and Spain according to EORTC QL Group guidelines. Twenty relevant QL issues were generated from the literature and interviews with health professionals (n=24) and patients (n=58). This produced a 24 item provisional module. Further testing in 115 patients resulted in the QLQ-STO22, containing 22 questions, conceptualised into five scales and four single items, related to disease symptoms, treatment side-effects and emotional issues specific to gastric cancer. The use of the QLQ-C30 supplemented by the QLQ-STO22 will provide a comprehensive QL measure for international trials in gastric cancer.

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Citation

Vickery, C.W., Blazeby, J.M., Conroy, T., Arraras, J., Sezer, O., Koller, M., Rosemeyer, D., Johnson, C.D. and Alderson, D. (2001) Development of an EORTC disease-specific quality of life module for use in patients with gastric cancer European Journal of Cancer, 37, (8), pp. 966-971. (doi:10.1016/S0959-8049(00)00417-2).

More information

Published date: 2001
Keywords: gastric neoplasm, quality of life, questionnaire, EORTC QLQ-C30, EORTC QLQ-STO22

Identifiers

Local EPrints ID: 26653
URI: http://eprints.soton.ac.uk/id/eprint/26653
ISSN: 0959-8049
PURE UUID: 7e0146c9-bbd4-4286-b9a5-25a1f432e0e4

Catalogue record

Date deposited: 24 Apr 2006
Last modified: 17 Jul 2017 16:06

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Contributors

Author: C.W. Vickery
Author: J.M. Blazeby
Author: T. Conroy
Author: J. Arraras
Author: O. Sezer
Author: M. Koller
Author: D. Rosemeyer
Author: C.D. Johnson
Author: D. Alderson

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