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On-chip electrical impedance tomography for 2D imaging of cells

On-chip electrical impedance tomography for 2D imaging of cells
On-chip electrical impedance tomography for 2D imaging of cells
Electrical impedance spectroscopy (EIS) is a high speed, non-invasive and label-free technique to characterize the dielectric properties of biological cells. Impedance-based microfluidic cytometers allow fast and accurate analysis (identification and differentiation) of single cells. The electrical properties of the cell constructs can also be characterized using other impedance measurement techniques, such as electric cell-substrate impedance sensing (ECIS). However these measurements are generally performed only in 1 dimension (between the excitation electrode and the sensing electrode). Electrical impedance tomography (EIT) extends the measurements to 2 or 3 dimensions, where measurements are taken across multiple electrodes. The method can be used to generate “images” of conductivity/resistivity distribution inside a sample by performing the measurements on the periphery of the sample. In our work, a miniaturized EIT system is used to image a multi-nucleated cell-Physarum polycephalum in culture.
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Tsuda, Soichiro
85070e3b-3f9b-4183-ac62-13e273eee0a8
Zauner, Klaus-Peter
c8b22dbd-10e6-43d8-813b-0766f985cc97
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
Sun, Tao
b2f8e932-a7e6-4fe7-94dd-5c4ce725eacb
Tsuda, Soichiro
85070e3b-3f9b-4183-ac62-13e273eee0a8
Zauner, Klaus-Peter
c8b22dbd-10e6-43d8-813b-0766f985cc97
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174

Sun, Tao, Tsuda, Soichiro, Zauner, Klaus-Peter and Morgan, Hywel (2008) On-chip electrical impedance tomography for 2D imaging of cells. 12th annual European conference on micro & nanoscale technologies for biosciences, Switzerland. 16 - 19 Nov 2008.

Record type: Conference or Workshop Item (Poster)

Abstract

Electrical impedance spectroscopy (EIS) is a high speed, non-invasive and label-free technique to characterize the dielectric properties of biological cells. Impedance-based microfluidic cytometers allow fast and accurate analysis (identification and differentiation) of single cells. The electrical properties of the cell constructs can also be characterized using other impedance measurement techniques, such as electric cell-substrate impedance sensing (ECIS). However these measurements are generally performed only in 1 dimension (between the excitation electrode and the sensing electrode). Electrical impedance tomography (EIT) extends the measurements to 2 or 3 dimensions, where measurements are taken across multiple electrodes. The method can be used to generate “images” of conductivity/resistivity distribution inside a sample by performing the measurements on the periphery of the sample. In our work, a miniaturized EIT system is used to image a multi-nucleated cell-Physarum polycephalum in culture.

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More information

Published date: November 2008
Additional Information: Event Dates: 16th -19th, November, 2008
Venue - Dates: 12th annual European conference on micro & nanoscale technologies for biosciences, Switzerland, 2008-11-16 - 2008-11-19
Organisations: Agents, Interactions & Complexity, Nanoelectronics and Nanotechnology

Identifiers

Local EPrints ID: 266906
URI: https://eprints.soton.ac.uk/id/eprint/266906
PURE UUID: 8a4a0885-6df7-4dba-b847-1dcafcabfdbd
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676

Catalogue record

Date deposited: 11 Nov 2008 12:12
Last modified: 06 Jun 2018 12:45

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Contributors

Author: Tao Sun
Author: Soichiro Tsuda
Author: Klaus-Peter Zauner
Author: Hywel Morgan ORCID iD

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