Detection of DNA-gold nanoparticle hybrids on patterned surfaces


Weld, A.M., Yin, H.B. and Melvin, T. (2004) Detection of DNA-gold nanoparticle hybrids on patterned surfaces At Postgraduate Conference on Biomedical Engineering and Medical Physics (PGBIOMED'04).

Download

[img] PDF 2946.pdf - Other
Download (194kB)

Description/Abstract

An optical diffraction based sensor has been developed for the detection of DNA-gold nanoparticle hybrids. Silicon substrates were patterned with oligonucleotide sequences in the form of a one-dimensional diffraction grating. Complementary sequences are detected by hybridisation with an oligonucleotide functionalised gold nanoparticle label. Detection of the gold nanoparticles is achieved by examining the diffraction efficiency of the diffraction gratings formed by laser illumination.

Item Type: Conference or Workshop Item (Paper)
Venue - Dates: Postgraduate Conference on Biomedical Engineering and Medical Physics (PGBIOMED'04), 2004-08-01
Related URLs:
Organisations: Optoelectronics Research Centre
ePrint ID: 267947
Date :
Date Event
August 2004e-pub ahead of print
Date Deposited: 24 Sep 2009 10:19
Last Modified: 17 Apr 2017 18:40
Further Information:Google Scholar
URI: http://eprints.soton.ac.uk/id/eprint/267947

Actions (login required)

View Item View Item