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Food allergy in children

Food allergy in children
Food allergy in children
Food allergy is being increasingly recognised with the highest prevalence being in preschool children. Pathogenesis varies so diagnosis rests on careful history and clinical examination, appropriate use of skin prick and serum-specific IgE testing, food challenge, and supervised elimination diets. A double blind placebo controlled food challenge is the gold standard diagnostic test. Avoidance of the allergenic food is the key towards successful management. IgE mediated food allergy may present as a potentially fatal anaphylactic reaction, and management consists of the appropriate use of adrenaline (epinephrine) and supportive measures. Sensitisation remains a key target for intervention. Disease modifying agents are currently under trial for managing difficult allergies. Management requires a multidisciplinary approach and follow up.

food allergy, IgE, multidisciplinary approach, skin prick testing, food specific IgE, double blinded oral challenge, epinephrine, auto-injectors, immunotherapy, adrenaline
0032-5473
693-701
Baral, V.R.
b7b3af56-0857-442b-9659-ab5d889b0b96
Hourihane, J.O'B.
9242e579-5036-45a2-8e0a-f1f8f3d0ad76
Baral, V.R.
b7b3af56-0857-442b-9659-ab5d889b0b96
Hourihane, J.O'B.
9242e579-5036-45a2-8e0a-f1f8f3d0ad76

Baral, V.R. and Hourihane, J.O'B. (2005) Food allergy in children. Postgraduate Medical Journal, 81 (961), 693-701. (doi:10.1136/pgmj.2004.030288).

Record type: Article

Abstract

Food allergy is being increasingly recognised with the highest prevalence being in preschool children. Pathogenesis varies so diagnosis rests on careful history and clinical examination, appropriate use of skin prick and serum-specific IgE testing, food challenge, and supervised elimination diets. A double blind placebo controlled food challenge is the gold standard diagnostic test. Avoidance of the allergenic food is the key towards successful management. IgE mediated food allergy may present as a potentially fatal anaphylactic reaction, and management consists of the appropriate use of adrenaline (epinephrine) and supportive measures. Sensitisation remains a key target for intervention. Disease modifying agents are currently under trial for managing difficult allergies. Management requires a multidisciplinary approach and follow up.

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More information

Published date: 2005
Keywords: food allergy, IgE, multidisciplinary approach, skin prick testing, food specific IgE, double blinded oral challenge, epinephrine, auto-injectors, immunotherapy, adrenaline

Identifiers

Local EPrints ID: 26927
URI: http://eprints.soton.ac.uk/id/eprint/26927
ISSN: 0032-5473
PURE UUID: c2bb5128-2f89-416a-8464-a99a399b4e11

Catalogue record

Date deposited: 25 Apr 2006
Last modified: 15 Jul 2019 19:13

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