The University of Southampton
University of Southampton Institutional Repository

Comparison of the allergenicity of Actinidia deliciosa (kiwi fruit) and Actinidia chinensis (gold kiwi)

Lucas, Jane S., Lewis, Stella A., Trewin, Jennifer B., Grimshaw, Kate E.C., Warner, John O. and Hourihane, Jonathan O'B. (2005) Comparison of the allergenicity of Actinidia deliciosa (kiwi fruit) and Actinidia chinensis (gold kiwi) Pediatric Allergy and Immunology, 16, (8), pp. 647-654. (doi:10.1111/j.1399-3038.2005.00330.x).

Record type: Article

Abstract

Actinidia chinensis (gold kiwi) is a newly available fruit which has been shown to have in vitro immunoglobulin E (IgE) cross-reactivity with green kiwi. This is the first study to investigate clinical reactivity of gold kiwi. Five patients clinically allergic to green kiwi were investigated by skin test and double-blind placebo controlled food challenge (DBPCFC) with gold kiwi fruit. IgE-binding patterns of individual sera from the five challenged patients and a pool of sera from a further nine patients with kiwi allergy were compared in the two fruits by Western blotting. Cross reactivity of proteins in the two fruits was assessed by inhibition of immunoblots and by IgE enzyme-linked immunosorbent assay (ELISA) inhibition. Four of the five patients had a positive DBPCFC to gold kiwi. Western blotting showed marked differences in the allergen patterns of green and gold kiwi. However, inhibition of the immunoblots and ELISA assay reveals extensive inhibition of IgE binding to proteins in each fruit by the alternative species. Gold kiwi fruit is allergenic and patients allergic to green kiwi are at risk of reacting to the gold kiwi fruit. Despite having different protein profiles and IgE-binding patterns, the two species have proteins that extensively cross-inhibit the binding to IgE.

Full text not available from this repository.

More information

Published date: 2005
Keywords: actinidia, kiwi fruit, allergens, double blind food challenge, immunoglobulin E, skin tests, sodium dodecylsulphate-polyacrylamide gel electrophoresis

Identifiers

Local EPrints ID: 27241
URI: http://eprints.soton.ac.uk/id/eprint/27241
ISSN: 0905-6157
PURE UUID: 200c7fe6-6191-4bd1-a645-274e4935b95b

Catalogue record

Date deposited: 27 Apr 2006
Last modified: 17 Jul 2017 16:05

Export record

Altmetrics

Contributors

Author: Jane S. Lucas
Author: Stella A. Lewis
Author: Jennifer B. Trewin
Author: John O. Warner
Author: Jonathan O'B. Hourihane

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×