Single region linkage analyses of asthma: description of data sets
Single region linkage analyses of asthma: description of data sets
Linkage (genotypic) data from the 5q31-33 candidate region for asthma were contributed to Genetic Analysis Workshop 12 by members of the International Consortium on Asthma Genetics (COAG). Data came from five independent studies sampled from five countries. Genotypic data for a total of 26 markers were available, although the number of markers typed in each data set varied. Phenotypic and genotypic data was available from a total of 569 families and 3,175 subjects. The phenotypic data available varied among the studies; however information regarding physician-diagnosed asthma and total serum IgE levels was available in all five studies. This paper describes the ascertainment, data collection methods, phenotypic data, and genotypic data available for the single linkage region analyses undertaken for Genetic Analysis Workshop 12.
9-15
Palmer, L.J.
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Cookson, W.O.
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Deichmann, K.A.
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Holloway, J.W.
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Laitinen, T.
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2001
Palmer, L.J.
b91d6236-22d5-405b-a653-bb831ae3002f
Cookson, W.O.
ee516784-e936-4edd-bd5f-064d8b45e977
Deichmann, K.A.
180f71cd-9084-4c56-86b6-779f8433c115
Holloway, J.W.
4bbd77e6-c095-445d-a36b-a50a72f6fe1a
Laitinen, T.
d390e6e7-6202-42f3-a680-95f81c4ae300
Palmer, L.J., Cookson, W.O., Deichmann, K.A., Holloway, J.W. and Laitinen, T.
(2001)
Single region linkage analyses of asthma: description of data sets.
Genetic Epidemiology, 21 (Supp 1), .
Abstract
Linkage (genotypic) data from the 5q31-33 candidate region for asthma were contributed to Genetic Analysis Workshop 12 by members of the International Consortium on Asthma Genetics (COAG). Data came from five independent studies sampled from five countries. Genotypic data for a total of 26 markers were available, although the number of markers typed in each data set varied. Phenotypic and genotypic data was available from a total of 569 families and 3,175 subjects. The phenotypic data available varied among the studies; however information regarding physician-diagnosed asthma and total serum IgE levels was available in all five studies. This paper describes the ascertainment, data collection methods, phenotypic data, and genotypic data available for the single linkage region analyses undertaken for Genetic Analysis Workshop 12.
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Published date: 2001
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Local EPrints ID: 27303
URI: http://eprints.soton.ac.uk/id/eprint/27303
ISSN: 0741-0395
PURE UUID: 7c5da560-0860-498d-80b9-7d77c7661d03
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Date deposited: 04 Aug 2008
Last modified: 08 Jan 2022 02:46
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Author:
L.J. Palmer
Author:
W.O. Cookson
Author:
K.A. Deichmann
Author:
T. Laitinen
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