A comparison of six and 12 PUVA treatments in the prophylaxis of polymorphic light eruption
A comparison of six and 12 PUVA treatments in the prophylaxis of polymorphic light eruption
Polymorphic light eruption (PLE) is a common condition for which the most effective treatment is prophylactic phototherapy. This is traditionally given in courses of approximately 12–15 exposures. We compared the effect of six and 12 treatments of psoralen-UVA (PUVA) therapy, in the prophylaxis of PLE, in a side-to-side within-patient comparison pilot study. In six out of eight patients, six treatments provided as much protection as 12 treatments. Five of these six patients had reported relatively mild disease in the previous year, in comparison to the other two patients. In view of the inconvenience and increased incidence of adverse effects associated with long treatment courses, we recommend the use of short courses, particularly in patients who are relatively mildly affected.
141-143
Palmer, R.A.
fdaf31be-56c5-478d-b14b-2f30e0d81af3
Friedmann, P.S.
d50bac23-f3ec-4493-8fa0-fa126cbeba88
2004
Palmer, R.A.
fdaf31be-56c5-478d-b14b-2f30e0d81af3
Friedmann, P.S.
d50bac23-f3ec-4493-8fa0-fa126cbeba88
Palmer, R.A. and Friedmann, P.S.
(2004)
A comparison of six and 12 PUVA treatments in the prophylaxis of polymorphic light eruption.
Clinical and Experimental Dermatology, 29 (2), .
(doi:10.1111/j.1365-2230.2004.01484.x).
Abstract
Polymorphic light eruption (PLE) is a common condition for which the most effective treatment is prophylactic phototherapy. This is traditionally given in courses of approximately 12–15 exposures. We compared the effect of six and 12 treatments of psoralen-UVA (PUVA) therapy, in the prophylaxis of PLE, in a side-to-side within-patient comparison pilot study. In six out of eight patients, six treatments provided as much protection as 12 treatments. Five of these six patients had reported relatively mild disease in the previous year, in comparison to the other two patients. In view of the inconvenience and increased incidence of adverse effects associated with long treatment courses, we recommend the use of short courses, particularly in patients who are relatively mildly affected.
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Published date: 2004
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Local EPrints ID: 27306
URI: http://eprints.soton.ac.uk/id/eprint/27306
ISSN: 0307-6938
PURE UUID: 35b93d19-410f-4874-94fa-2bf3bb224bc2
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Date deposited: 26 Apr 2006
Last modified: 15 Mar 2024 07:17
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Author:
R.A. Palmer
Author:
P.S. Friedmann
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