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Towards molecular computing: co-development of microfluidic devices and chemical reaction media

King, Philip, Corsi, Josephine C., Pan, Ben-Hong, Morgan, Hywel, de Planque, Maurits R.R. and Zauner, Klaus-Peter (2012) Towards molecular computing: co-development of microfluidic devices and chemical reaction media BioSystems, 109, (1), pp. 18-23. (doi:10.1016/j.biosystems.2012.01.003).

Record type: Article


Microfluidics provides a powerful technology for both the production of molecular computing components and for the implementation of molecular computing architectures. The potential commercial applications of microfluidics drive rapid progress in this field—but at the same time focus interest on materials that are compatible with physiological aqueous conditions. For engineering applications that consider a broader range of physico-chemical conditions the narrow set of established materials for microfluidics can be a challenge. As a consequence of the large surface to volume ratio inherent in microfluidic technology the material of the device can greatly affect the chemistry in the channels of the device. In practice it is necessary to co-develop the chemical medium to be used in the device together with the microfluidic devices. We describe this process for a molecular computing architecture that makes use of excitable lipid-coated droplets of Belousov–Zhabotinsky reaction medium as its active processing components. We identify fluoropolymers with low melting temperature as a suitable substrate for microfluidics to be used in conjunction with Belousov–Zhabotinsky droplets in decane.

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Accepted/In Press date: 4 January 2012
Published date: 9 June 2012
Organisations: Nanoelectronics and Nanotechnology, Agents, Interactions & Complexity


Local EPrints ID: 273062
ISSN: 0303-2647
PURE UUID: 28a6185e-b2b4-4db2-b304-060500e1ceb0
ORCID for Hywel Morgan: ORCID iD
ORCID for Maurits R.R. de Planque: ORCID iD

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Date deposited: 13 Dec 2011 09:58
Last modified: 18 Jul 2017 06:17

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Author: Philip King
Author: Josephine C. Corsi
Author: Ben-Hong Pan
Author: Hywel Morgan ORCID iD
Author: Klaus-Peter Zauner

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