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Matrix metalloproteinases and the gut - new roles for old enzymes

Matrix metalloproteinases and the gut - new roles for old enzymes
Matrix metalloproteinases and the gut - new roles for old enzymes
Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and cancer. Recent data suggest that MMPs are involved in tissue injury and healing in the human gut.
1471-4892
546-550
Pender, Sylvia L. F.
62528b03-ec42-41bb-80fe-48454c2c5242
MacDonald, Thomas T
e2ed80d6-3d63-452b-aada-566afc286286
Pender, Sylvia L. F.
62528b03-ec42-41bb-80fe-48454c2c5242
MacDonald, Thomas T
e2ed80d6-3d63-452b-aada-566afc286286

Pender, Sylvia L. F. and MacDonald, Thomas T (2004) Matrix metalloproteinases and the gut - new roles for old enzymes. Current Opinion in Pharmacology, 4 (6), 546-550. (doi:10.1016/j.coph.2004.06.005).

Record type: Article

Abstract

Matrix metalloproteinases (MMPs) are a family of neutral proteases with the ability to degrade all components of extracellular matrix. To date, more than 24 different human MMPs have been identified. MMP activity is important in diseases such as arthritis, atherosclerosis, periodontal diseases and cancer. Recent data suggest that MMPs are involved in tissue injury and healing in the human gut.

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Published date: 2004

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Local EPrints ID: 27322
URI: http://eprints.soton.ac.uk/id/eprint/27322
ISSN: 1471-4892
PURE UUID: 4224b77d-64e7-480e-b2b4-73d2fd5ece33
ORCID for Sylvia L. F. Pender: ORCID iD orcid.org/0000-0001-6332-0333

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Date deposited: 25 Apr 2006
Last modified: 16 Mar 2024 03:19

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Author: Thomas T MacDonald

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