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Early life exposure to dietary and inhalant allergens

Early life exposure to dietary and inhalant allergens
Early life exposure to dietary and inhalant allergens
Increasing evidence points to early life, including fetal life, as being a critical time period during which the infant's allergic fate may be determined. However, initial antigen priming in utero necessitates fetal exposure to maternally derived allergen. This article reviews our current knowledge regarding materno-fetal allergen transfer in vivo and reflects on mechanisms by which this exposure might exert immunomodulatory influences on the developing immune system.
allergens, diet, pregnancy
0905-6157
14-18
Vance, Gillian H.S.
5a81a019-0f8f-4437-b559-d4b0996ce249
Holloway, Judith A.
f22f45f3-6fc8-4a4c-bc6c-24add507037c
Vance, Gillian H.S.
5a81a019-0f8f-4437-b559-d4b0996ce249
Holloway, Judith A.
f22f45f3-6fc8-4a4c-bc6c-24add507037c

Vance, Gillian H.S. and Holloway, Judith A. (2002) Early life exposure to dietary and inhalant allergens. Pediatric Allergy and Immunology, 13 (s15), 14-18. (doi:10.1034/j.1399-3038.13.s.15.5.x).

Record type: Article

Abstract

Increasing evidence points to early life, including fetal life, as being a critical time period during which the infant's allergic fate may be determined. However, initial antigen priming in utero necessitates fetal exposure to maternally derived allergen. This article reviews our current knowledge regarding materno-fetal allergen transfer in vivo and reflects on mechanisms by which this exposure might exert immunomodulatory influences on the developing immune system.

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Published date: 2002
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Keywords: allergens, diet, pregnancy

Identifiers

Local EPrints ID: 27457
URI: http://eprints.soton.ac.uk/id/eprint/27457
DOI: doi:10.1034/j.1399-3038.13.s.15.5.x
ISSN: 0905-6157
PURE UUID: 0ddd38e3-8dff-41ed-b02d-878cf3167bfa
ORCID for Judith A. Holloway: ORCID iD orcid.org/0000-0002-2268-3071

Catalogue record

Date deposited: 28 Apr 2006
Last modified: 16 Mar 2024 03:13

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Contributors

Author: Gillian H.S. Vance
Author: Judith A. Holloway ORCID iD

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