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No association between akathisia or Parkinsonism and suicidality in treatment-resistant schizophrenia

No association between akathisia or Parkinsonism and suicidality in treatment-resistant schizophrenia
No association between akathisia or Parkinsonism and suicidality in treatment-resistant schizophrenia
Akathisia and drug-induced Parkinsonism have traditionally been associated with depression and suicidality based on case study evidence. In this subanalysis, patients with treatment resistant schizophrenia were rated on the Comprehensive Psychopathological Rating Scale, Barnes Akathisia Scale and Simpson-Angus extrapyramidal side-effect scale at two time points (n = 86 at first assessment; n = 67 at second assessment). At no time point was there any significant relationship between akathisia and depression/suicidality or distress associated with akathisia and Parkinsonism with suicidality. These preliminary findings warrant further investigation.
akathisia, extrapyramidal sideeffects, risk, patients, drug-induced akathisia, treatment, time, scale, depression, resistant, suicide, London, drug-induced parkinsonism, England, therapy, schizophrenia
0269-8811
384-387
Hansen, Lars
c07afee9-a9d5-4d89-9703-2a603a23b8fe
Jones, Roland M.
7f844991-0ae8-4ad8-8742-eddd3a2675de
Kingdon, David
14cdc422-10b4-4b2d-88ec-24fde5f4329b
Hansen, Lars
c07afee9-a9d5-4d89-9703-2a603a23b8fe
Jones, Roland M.
7f844991-0ae8-4ad8-8742-eddd3a2675de
Kingdon, David
14cdc422-10b4-4b2d-88ec-24fde5f4329b

Hansen, Lars, Jones, Roland M. and Kingdon, David (2004) No association between akathisia or Parkinsonism and suicidality in treatment-resistant schizophrenia. Journal of Psychopharmacology, 18 (3), 384-387. (doi:10.1177/026988110401800309).

Record type: Article

Abstract

Akathisia and drug-induced Parkinsonism have traditionally been associated with depression and suicidality based on case study evidence. In this subanalysis, patients with treatment resistant schizophrenia were rated on the Comprehensive Psychopathological Rating Scale, Barnes Akathisia Scale and Simpson-Angus extrapyramidal side-effect scale at two time points (n = 86 at first assessment; n = 67 at second assessment). At no time point was there any significant relationship between akathisia and depression/suicidality or distress associated with akathisia and Parkinsonism with suicidality. These preliminary findings warrant further investigation.

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More information

Published date: 2004
Keywords: akathisia, extrapyramidal sideeffects, risk, patients, drug-induced akathisia, treatment, time, scale, depression, resistant, suicide, London, drug-induced parkinsonism, England, therapy, schizophrenia

Identifiers

Local EPrints ID: 27583
URI: http://eprints.soton.ac.uk/id/eprint/27583
ISSN: 0269-8811
PURE UUID: dc1f061d-f541-4f9a-89f8-3751696b1ca5

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Date deposited: 27 Apr 2006
Last modified: 08 Jan 2022 15:51

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Contributors

Author: Lars Hansen
Author: Roland M. Jones
Author: David Kingdon

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