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A new role for astrocytes: ?-amyloid homeostasis and degradation

Nicoll, James A.R. and Weller, Roy O. (2003) A new role for astrocytes: ?-amyloid homeostasis and degradation Trends in Molecular Medicine, 9, (7), pp. 281-282. (doi:10.1016/S1471-4914(03)00109-6).

Record type: Article


Accumulation of ?-amyloid protein (A?) in the brain is believed to play a key role in the pathogenesis of Alzheimer's disease (AD). There is evidence that A? accumulation might result from decreased elimination from the brain as well as from increased production, and recent work has suggested that astrocytes could have a role in A? degradation. This might lead to a better understanding of AD pathogenesis and possibly to new therapeutic avenues.

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Published date: 2003


Local EPrints ID: 27674
ISSN: 1471-4914
PURE UUID: c6b3d514-5b65-4052-957a-0a7cd1e3b79e
ORCID for James A.R. Nicoll: ORCID iD

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Date deposited: 28 Apr 2006
Last modified: 17 Jul 2017 16:04

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