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Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage

Record type: Article

Cerebral vasospasm is a recognised but poorly understood complication for many patients who have aneurysmal subarachnoid haemorrhage and can lead to delayed ischaemic neurological deficit (stroke). Morbidity and mortality rates for vasospasm are high despite improvements in management. Since the middle of the 1970s, much has been written about the treatment of cerebral vasospasm. Hypervolaemia, hypertension, and haemodilution (triple-H) therapy in an intensive-care setting has been shown in some studies to improve outcome and is an accepted means of treatment, although a randomised controlled trial has never been undertaken. In this review, the rationale for this approach will be discussed, alongside new thoughts and future prospects for the management of this complex disorder.

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Citation

Sen, Jon, Belli, Antonio, Albon, Helen, Morgan, Laleh, Petzold, Axel and Kitchen, Neil (2003) Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage Lancet Neurology, 2, (10), pp. 614-620. (doi:10.1016/S1474-4422(03)00531-3).

More information

Published date: October 2003

Identifiers

Local EPrints ID: 27710
URI: http://eprints.soton.ac.uk/id/eprint/27710
ISSN: 1474-4422
PURE UUID: e1875f95-75a3-492d-a19d-d3119fcda58e

Catalogue record

Date deposited: 25 Apr 2006
Last modified: 17 Jul 2017 16:03

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Contributors

Author: Jon Sen
Author: Antonio Belli
Author: Helen Albon
Author: Laleh Morgan
Author: Axel Petzold
Author: Neil Kitchen

University divisions


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