The University of Southampton
University of Southampton Institutional Repository

Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage

Sen, Jon, Belli, Antonio, Albon, Helen, Morgan, Laleh, Petzold, Axel and Kitchen, Neil (2003) Triple-H therapy in the management of aneurysmal subarachnoid haemorrhage Lancet Neurology, 2, (10), pp. 614-620. (doi:10.1016/S1474-4422(03)00531-3).

Record type: Article


Cerebral vasospasm is a recognised but poorly understood complication for many patients who have aneurysmal subarachnoid haemorrhage and can lead to delayed ischaemic neurological deficit (stroke). Morbidity and mortality rates for vasospasm are high despite improvements in management. Since the middle of the 1970s, much has been written about the treatment of cerebral vasospasm. Hypervolaemia, hypertension, and haemodilution (triple-H) therapy in an intensive-care setting has been shown in some studies to improve outcome and is an accepted means of treatment, although a randomised controlled trial has never been undertaken. In this review, the rationale for this approach will be discussed, alongside new thoughts and future prospects for the management of this complex disorder.

Full text not available from this repository.

More information

Published date: October 2003


Local EPrints ID: 27710
ISSN: 1474-4422
PURE UUID: e1875f95-75a3-492d-a19d-d3119fcda58e

Catalogue record

Date deposited: 25 Apr 2006
Last modified: 17 Jul 2017 16:03

Export record



Author: Jon Sen
Author: Antonio Belli
Author: Helen Albon
Author: Laleh Morgan
Author: Axel Petzold
Author: Neil Kitchen

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.