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Suicide in depressive disorders: a retrospective case-control study of 127 suicides

Suicide in depressive disorders: a retrospective case-control study of 127 suicides
Suicide in depressive disorders: a retrospective case-control study of 127 suicides
Background: Depressive disorders are associated with a significant risk of suicide. Inpatient status and recent discharge from hospital have been identified as times of high risk of suicide within the course of illness.
Method: A matched retrospective case control study of 127 patients with depression requiring inpatient care who died by suicide as inpatients or in the 12 months following discharge from hospital. Single and multivariable conditional logistic regression identified independent risk and protective factors for suicide.
Results: A history of deliberate self harm is a significant risk factor for suicide in patients with depression (OR 6.96; 95% CI 3.41–14.19), as is living alone (OR 2.11; 95% CI 1.15–3.87) and paid employment (OR 2.80; 95% CI 1.48–5.32). Admission to hospital during social crisis is associated with a reduction in suicide risk (OR 0.43; 95% CI 0.24–0.75).
Limitations: This is a retrospective case-control study, using clinical data not originally collected for research purposes.
Conclusions: General population risk factors for suicide are less predictive of suicide in patients with depression requiring inpatient treatment. Clinicians need to be aware of factors which increase or reduce the risk of suicide in this group.
suicide, depression, affective disorder, in-patient care
0165-0327
107-113
Sinclair, Julia M.A.
be3e54d5-c6da-4950-b0ba-3cb8cdcab13c
Harriss, Louise
8746aca7-7cbf-4b01-81dd-e1c3edb66dfc
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
King, Elizabeth A.
df3edffe-d232-4d6a-933f-37d8341611a7
Sinclair, Julia M.A.
be3e54d5-c6da-4950-b0ba-3cb8cdcab13c
Harriss, Louise
8746aca7-7cbf-4b01-81dd-e1c3edb66dfc
Baldwin, David S.
1beaa192-0ef1-4914-897a-3a49fc2ed15e
King, Elizabeth A.
df3edffe-d232-4d6a-933f-37d8341611a7

Sinclair, Julia M.A., Harriss, Louise, Baldwin, David S. and King, Elizabeth A. (2005) Suicide in depressive disorders: a retrospective case-control study of 127 suicides. Journal of Affective Disorders, 87 (1), 107-113. (doi:10.1016/j.jad.2005.03.001).

Record type: Article

Abstract

Background: Depressive disorders are associated with a significant risk of suicide. Inpatient status and recent discharge from hospital have been identified as times of high risk of suicide within the course of illness.
Method: A matched retrospective case control study of 127 patients with depression requiring inpatient care who died by suicide as inpatients or in the 12 months following discharge from hospital. Single and multivariable conditional logistic regression identified independent risk and protective factors for suicide.
Results: A history of deliberate self harm is a significant risk factor for suicide in patients with depression (OR 6.96; 95% CI 3.41–14.19), as is living alone (OR 2.11; 95% CI 1.15–3.87) and paid employment (OR 2.80; 95% CI 1.48–5.32). Admission to hospital during social crisis is associated with a reduction in suicide risk (OR 0.43; 95% CI 0.24–0.75).
Limitations: This is a retrospective case-control study, using clinical data not originally collected for research purposes.
Conclusions: General population risk factors for suicide are less predictive of suicide in patients with depression requiring inpatient treatment. Clinicians need to be aware of factors which increase or reduce the risk of suicide in this group.

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More information

Published date: 2005
Keywords: suicide, depression, affective disorder, in-patient care

Identifiers

Local EPrints ID: 27714
URI: http://eprints.soton.ac.uk/id/eprint/27714
ISSN: 0165-0327
PURE UUID: 7ba14b53-fa44-44c5-8ba0-a5ab44e6537c
ORCID for Julia M.A. Sinclair: ORCID iD orcid.org/0000-0002-1905-2025
ORCID for David S. Baldwin: ORCID iD orcid.org/0000-0003-3343-0907

Catalogue record

Date deposited: 25 Apr 2006
Last modified: 09 Jan 2022 02:52

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Contributors

Author: Louise Harriss
Author: Elizabeth A. King

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