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Broadband measurements of the frequency dependence of attenuation coefficient and velocity in amniotic fluid, urine and human serum albumin solutions

Broadband measurements of the frequency dependence of attenuation coefficient and velocity in amniotic fluid, urine and human serum albumin solutions
Broadband measurements of the frequency dependence of attenuation coefficient and velocity in amniotic fluid, urine and human serum albumin solutions
The frequency dependence of attenuation coefficient in amniotic fluid, urine and 4.5% and 20% human serum albumin solutions over the frequency range 5 MHz to 25 MHz was measured at both room temperature and physiological temperature using a variable path length technique. A 15 MHz (13 mm diameter) transducer was used to produce a broadband single-cycle pulse and a 4 mm diameter bilaminar polyvinylidene difluoride membrane hydrophone was used to detect the attenuated pulse. Standard time-of-flight measurement techniques were used to measure the acoustic velocity in the same fluid samples. At physiological temperature, the attenuation coefficients in amniotic fluid, urine and 4.5% and 20% human albumin solution were found to be 0.0053 f(1.65), 0.0047 f(1.67), 0.019 f(1.57) and 0.167 f(1.27) dB cm(-1), respectively, where f is in MHz. The velocities in amniotic fluid, urine and 4.5% human albumin solution at physiological temperature were found to be 1541.1 m s(-1) +/- 1.3 m s(-1), 1551.3 m s(-1) +/- 1.3 ms(-1) and 1547.3 m s(-1) +/- 1.0 m s(-1), respectively. The results provide unique data over the diagnostic and therapeutic ultrasonic frequency range that can be used as input data for theoretical models that attempt to simulate nonlinear pressure fields and temperature rises from medical ultrasonic transducers.
broadband measurements, attenuation coefficient, speed of sound, amniotic fluid, biological fluids
0301-5629
1375-81
Verma, Prashant K.
e301fff0-445d-40a2-9b98-10b0e33e38e5
Humphrey, Victor F.
23c9bd0c-7870-428f-b0dd-5ff158d22590
Duck, Francis A.
46fb1f23-a818-48a9-a377-d8faa5b75087
Verma, Prashant K.
e301fff0-445d-40a2-9b98-10b0e33e38e5
Humphrey, Victor F.
23c9bd0c-7870-428f-b0dd-5ff158d22590
Duck, Francis A.
46fb1f23-a818-48a9-a377-d8faa5b75087

Verma, Prashant K., Humphrey, Victor F. and Duck, Francis A. (2005) Broadband measurements of the frequency dependence of attenuation coefficient and velocity in amniotic fluid, urine and human serum albumin solutions. Ultrasound in Medicine & Biology, 31 (10), 1375-81. (doi:10.1016/j.ultrasmedbio.2005.06.003).

Record type: Article

Abstract

The frequency dependence of attenuation coefficient in amniotic fluid, urine and 4.5% and 20% human serum albumin solutions over the frequency range 5 MHz to 25 MHz was measured at both room temperature and physiological temperature using a variable path length technique. A 15 MHz (13 mm diameter) transducer was used to produce a broadband single-cycle pulse and a 4 mm diameter bilaminar polyvinylidene difluoride membrane hydrophone was used to detect the attenuated pulse. Standard time-of-flight measurement techniques were used to measure the acoustic velocity in the same fluid samples. At physiological temperature, the attenuation coefficients in amniotic fluid, urine and 4.5% and 20% human albumin solution were found to be 0.0053 f(1.65), 0.0047 f(1.67), 0.019 f(1.57) and 0.167 f(1.27) dB cm(-1), respectively, where f is in MHz. The velocities in amniotic fluid, urine and 4.5% human albumin solution at physiological temperature were found to be 1541.1 m s(-1) +/- 1.3 m s(-1), 1551.3 m s(-1) +/- 1.3 ms(-1) and 1547.3 m s(-1) +/- 1.0 m s(-1), respectively. The results provide unique data over the diagnostic and therapeutic ultrasonic frequency range that can be used as input data for theoretical models that attempt to simulate nonlinear pressure fields and temperature rises from medical ultrasonic transducers.

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More information

Published date: 2005
Keywords: broadband measurements, attenuation coefficient, speed of sound, amniotic fluid, biological fluids

Identifiers

Local EPrints ID: 28398
URI: https://eprints.soton.ac.uk/id/eprint/28398
ISSN: 0301-5629
PURE UUID: e4e625c1-83c0-4b3b-b087-f47e4702f900
ORCID for Victor F. Humphrey: ORCID iD orcid.org/0000-0002-3580-5373

Catalogue record

Date deposited: 28 Apr 2006
Last modified: 06 Jun 2018 12:45

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