Mathematical models for the early detection and treatment of colorectal cancer
Mathematical models for the early detection and treatment of colorectal cancer
Colorectal cancer is a major cause of death for men and women in the Western world. When the cancer is detected through an awareness of the symptoms by a patient, typically it is at an advanced stage. It is possible to detect cancer at an early stage through screening and the marked differences in survival for early and late stages provide the incentive for the primary prevention or early detection of colorectal cancer. This paper considers mathematical models for colorectal cancer screening together with models for the treatment of patients. Illustrative results demonstrate that detailed attention to the processes involved in diseases, interventions and treatment enable us to combine data and expert knowledge from various sources. Thus a detailed operational model is a very useful tool in helping to make decisions about screening at national and local levels.
colorectal cancer, screening, health care modelling, simulation
101-109
Harper, P.
93a9f992-d1de-4748-b77a-00917cf3e879
Jones, S.
43516f9c-c999-4c10-86b6-43992e4e7a29
2005
Harper, P.
93a9f992-d1de-4748-b77a-00917cf3e879
Jones, S.
43516f9c-c999-4c10-86b6-43992e4e7a29
Harper, P. and Jones, S.
(2005)
Mathematical models for the early detection and treatment of colorectal cancer.
Health Care Management Science, 8 (2), .
(doi:10.1007/s10729-005-0393-7).
Abstract
Colorectal cancer is a major cause of death for men and women in the Western world. When the cancer is detected through an awareness of the symptoms by a patient, typically it is at an advanced stage. It is possible to detect cancer at an early stage through screening and the marked differences in survival for early and late stages provide the incentive for the primary prevention or early detection of colorectal cancer. This paper considers mathematical models for colorectal cancer screening together with models for the treatment of patients. Illustrative results demonstrate that detailed attention to the processes involved in diseases, interventions and treatment enable us to combine data and expert knowledge from various sources. Thus a detailed operational model is a very useful tool in helping to make decisions about screening at national and local levels.
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Published date: 2005
Keywords:
colorectal cancer, screening, health care modelling, simulation
Organisations:
Operational Research
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Local EPrints ID: 29709
URI: http://eprints.soton.ac.uk/id/eprint/29709
ISSN: 1386-9620
PURE UUID: 95cea31c-8f86-413b-86c8-be5c6f9d5df6
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Date deposited: 11 May 2006
Last modified: 15 Mar 2024 07:34
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Author:
P. Harper
Author:
S. Jones
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