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Natural killer cells: integrating diversity with function

Record type: Article

The key role of natural killer cells in many aspects of the immune response is now being recognized. The last decade has seen an exponential increase in our understanding of the workings of these cells. Receptor diversity is crucial in allowing natural killer cells to respond effectively to a variety of different pathogens. This article reviews aspects of natural killer cell diversity that combine to generate populations of functional natural killer cells that exist within both the individual and throughout the population at large.

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Citation

Cheent, Kuldeep and Khakoo, Salim I. (2009) Natural killer cells: integrating diversity with function Immunology, 126, (4), pp. 449-457. (doi:10.1111/j.1365-2567.2009.03045.x). (PMID:19278418).

More information

Published date: April 2009
Keywords: diversity, integration, KIR, NK cells, receptors, signalling
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 336185
URI: http://eprints.soton.ac.uk/id/eprint/336185
ISSN: 0019-2805
PURE UUID: 8ac34711-2c71-4545-9b2d-ff9f5c16bb07

Catalogue record

Date deposited: 16 Mar 2012 14:41
Last modified: 18 Jul 2017 06:09

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Contributors

Author: Kuldeep Cheent
Author: Salim I. Khakoo

University divisions


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