The University of Southampton
University of Southampton Institutional Repository

Management of hospital outbreaks of gastro-enteritis due to small round structured viruses

Management of hospital outbreaks of gastro-enteritis due to small round structured viruses
Management of hospital outbreaks of gastro-enteritis due to small round structured viruses
Small round structured viruses (SRSVs, Norwalk-like viruses, NLVs) are the most common
cause of outbreaks of gastro-enteritis in hospitals and also cause outbreaks in other settings such as schools,
hotels, nursing homes and cruise ships. Hospital outbreaks often lead to ward closure and major disruption
in hospital activity. Outbreaks usually affect both patients and staff, sometimes with attack rates in excess of
50%. For this reason, staff shortages can be severe, particularly if several wards are involved at the same
time. SRSVs may be spread by several routes: faecal–oral; vomiting/aerosols; food and water. Viruses may
be introduced into the ward environment by any of these routes and then propagated by person-to-person
spread. In an outbreak setting, the diagnosis can usually be made rapidly and confidently on clinical and
epidemiological grounds, particularly if vomiting is a prominent symptom. By the time an SRSV outbreak
has been recognized at ward level, most susceptible individuals will have been exposed to the virus and
infection control efforts must prioritize the prevention of spread of infection to other clinical areas by
containment of infected/exposed individuals (especially the prevention of patient and staff movements to
other areas), hand-hygiene and effective environmental decontamination.
This report of the Public Health Laboratory Service Viral Gastro-enteritis Working Group reviews the epidemiology
of outbreaks of infection due to SRSVs and makes recommendations for their management in the
hospital setting. The basic principles which underpin these recommendations will also be applicable to the
management of some community-based institutional outbreaks.
0195-6701
1-10
Chadwick, P. R.
d76748be-5b2a-43d1-9af6-471a86c1c74c
Beards, G.
788329ad-41d2-4516-af96-e856e9bb5fd8
Brown, D.
066e8669-5678-4f7c-96eb-e8e29a9a4cfb
Caul, E. O.
91f307fa-d4ba-43f7-829a-6a60b0827b12
Cheesbrough, J.
3fd2e384-fd82-415a-aeb4-b1a6aa535e59
Clarke, I. N.
ff6c9324-3547-4039-bb2c-10c0b3327a8b
Curry, A.
f6589489-ff60-40ee-98b0-bab9c1be4597
O'Brien, S.
d7d5bd8d-0d9a-4ece-b03a-426a9a433f61
Quigley, K.
94f6dfe0-f420-4a9b-966f-d185473d9bed
Sellwood, J.
c8d9af6a-af2a-42cb-96e8-26bcda0a9aee
Westmoreland, D.
e7edf61e-d974-4aa3-a4ff-da4607709875
Chadwick, P. R.
d76748be-5b2a-43d1-9af6-471a86c1c74c
Beards, G.
788329ad-41d2-4516-af96-e856e9bb5fd8
Brown, D.
066e8669-5678-4f7c-96eb-e8e29a9a4cfb
Caul, E. O.
91f307fa-d4ba-43f7-829a-6a60b0827b12
Cheesbrough, J.
3fd2e384-fd82-415a-aeb4-b1a6aa535e59
Clarke, I. N.
ff6c9324-3547-4039-bb2c-10c0b3327a8b
Curry, A.
f6589489-ff60-40ee-98b0-bab9c1be4597
O'Brien, S.
d7d5bd8d-0d9a-4ece-b03a-426a9a433f61
Quigley, K.
94f6dfe0-f420-4a9b-966f-d185473d9bed
Sellwood, J.
c8d9af6a-af2a-42cb-96e8-26bcda0a9aee
Westmoreland, D.
e7edf61e-d974-4aa3-a4ff-da4607709875

Chadwick, P. R., Beards, G., Brown, D., Caul, E. O., Cheesbrough, J., Clarke, I. N., Curry, A., O'Brien, S., Quigley, K., Sellwood, J. and Westmoreland, D. (2000) Management of hospital outbreaks of gastro-enteritis due to small round structured viruses. Journal of Hospital Infection, 45 (1), 1-10. (PMID:10833336)

Record type: Article

Abstract

Small round structured viruses (SRSVs, Norwalk-like viruses, NLVs) are the most common
cause of outbreaks of gastro-enteritis in hospitals and also cause outbreaks in other settings such as schools,
hotels, nursing homes and cruise ships. Hospital outbreaks often lead to ward closure and major disruption
in hospital activity. Outbreaks usually affect both patients and staff, sometimes with attack rates in excess of
50%. For this reason, staff shortages can be severe, particularly if several wards are involved at the same
time. SRSVs may be spread by several routes: faecal–oral; vomiting/aerosols; food and water. Viruses may
be introduced into the ward environment by any of these routes and then propagated by person-to-person
spread. In an outbreak setting, the diagnosis can usually be made rapidly and confidently on clinical and
epidemiological grounds, particularly if vomiting is a prominent symptom. By the time an SRSV outbreak
has been recognized at ward level, most susceptible individuals will have been exposed to the virus and
infection control efforts must prioritize the prevention of spread of infection to other clinical areas by
containment of infected/exposed individuals (especially the prevention of patient and staff movements to
other areas), hand-hygiene and effective environmental decontamination.
This report of the Public Health Laboratory Service Viral Gastro-enteritis Working Group reviews the epidemiology
of outbreaks of infection due to SRSVs and makes recommendations for their management in the
hospital setting. The basic principles which underpin these recommendations will also be applicable to the
management of some community-based institutional outbreaks.

Full text not available from this repository.

More information

Published date: May 2000
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 336235
URI: https://eprints.soton.ac.uk/id/eprint/336235
ISSN: 0195-6701
PURE UUID: 84c21d25-78ea-48de-808b-32750f15e39e
ORCID for I. N. Clarke: ORCID iD orcid.org/0000-0002-4938-1620

Catalogue record

Date deposited: 20 Mar 2012 11:12
Last modified: 06 Jun 2018 13:19

Export record

Contributors

Author: P. R. Chadwick
Author: G. Beards
Author: D. Brown
Author: E. O. Caul
Author: J. Cheesbrough
Author: I. N. Clarke ORCID iD
Author: A. Curry
Author: S. O'Brien
Author: K. Quigley
Author: J. Sellwood
Author: D. Westmoreland

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of https://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×