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The asthma control test(TM) (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey

The asthma control test(TM) (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey
The asthma control test(TM) (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey
AIMS: To evaluate whether the Asthma Control TestTM (ACT) score is predictive of Global Initiative for Asthma (GINA) guideline-defined classification levels of asthma control. The ACT is a validated, 5-item, patient-completed measure of asthma control with a recall period of four weeks. METHODS: Cross-sectional survey comparing ACT score and GINA classification of asthma control among 2949 patients attending primary care physicians and specialists in France, Germany, Italy, Spain, the UK, and the USA. RESULTS: The area under the receiver operating characteristics curve for ACT score predicting GINA control was 0.84 (95% CI 0.82–0.85). An ACT score of <19 (not well-controlled asthma) correctly predicted GINA-defined partly controlled/uncontrolled asthma 94% of the time, while an ACT score of >20 predicted GINA-defined controlled asthma 51% of the time, with kappa statistic of 0.42, representing moderate agreement. CONCLUSIONS: An ACT score <19 is useful for identifying patients with poorly controlled asthma as defined by GINA.

asthma, asthma control test, control, GINA, exacerbations, multinational survey, patient-completed outcome assessment
1471-4418
41-49
Thomas, M
997c78e0-3849-4ce8-b1bc-86ebbdee3953
Kay, S.
48a2ee19-d372-4a6b-9e0f-3be837de26cf
Pike, J.
a752c052-98ae-4c4c-967d-051bc9586219
Williams, A.
5906f63e-1283-4a30-9ec1-74d19d61b328
Rosenzweig, J.R.C.
00176ad8-e900-480f-8350-b3ed69804a5e
Hillyer, E.V.
9f6609c8-3e76-476e-8294-d035ecab0d1f
Price, D.
7534eb51-9b20-4840-9604-f34a428c855c
Thomas, M
997c78e0-3849-4ce8-b1bc-86ebbdee3953
Kay, S.
48a2ee19-d372-4a6b-9e0f-3be837de26cf
Pike, J.
a752c052-98ae-4c4c-967d-051bc9586219
Williams, A.
5906f63e-1283-4a30-9ec1-74d19d61b328
Rosenzweig, J.R.C.
00176ad8-e900-480f-8350-b3ed69804a5e
Hillyer, E.V.
9f6609c8-3e76-476e-8294-d035ecab0d1f
Price, D.
7534eb51-9b20-4840-9604-f34a428c855c

Thomas, M, Kay, S., Pike, J., Williams, A., Rosenzweig, J.R.C., Hillyer, E.V. and Price, D. (2009) The asthma control test(TM) (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey. Primary Care Respiratory Journal, 18 (1), 41-49. (doi:10.4104/pcrj.2009.00010). (PMID:19240948)

Record type: Article

Abstract

AIMS: To evaluate whether the Asthma Control TestTM (ACT) score is predictive of Global Initiative for Asthma (GINA) guideline-defined classification levels of asthma control. The ACT is a validated, 5-item, patient-completed measure of asthma control with a recall period of four weeks. METHODS: Cross-sectional survey comparing ACT score and GINA classification of asthma control among 2949 patients attending primary care physicians and specialists in France, Germany, Italy, Spain, the UK, and the USA. RESULTS: The area under the receiver operating characteristics curve for ACT score predicting GINA control was 0.84 (95% CI 0.82–0.85). An ACT score of <19 (not well-controlled asthma) correctly predicted GINA-defined partly controlled/uncontrolled asthma 94% of the time, while an ACT score of >20 predicted GINA-defined controlled asthma 51% of the time, with kappa statistic of 0.42, representing moderate agreement. CONCLUSIONS: An ACT score <19 is useful for identifying patients with poorly controlled asthma as defined by GINA.

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More information

e-pub ahead of print date: 24 February 2009
Published date: March 2009
Keywords: asthma, asthma control test, control, GINA, exacerbations, multinational survey, patient-completed outcome assessment
Organisations: Primary Care & Population Sciences

Identifiers

Local EPrints ID: 337297
URI: https://eprints.soton.ac.uk/id/eprint/337297
ISSN: 1471-4418
PURE UUID: 108245ed-08b5-4734-a1a6-5456200874c3

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Date deposited: 23 Apr 2012 14:00
Last modified: 16 Jul 2019 22:07

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Contributors

Author: M Thomas
Author: S. Kay
Author: J. Pike
Author: A. Williams
Author: J.R.C. Rosenzweig
Author: E.V. Hillyer
Author: D. Price

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