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Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD pediatric official positions

Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD pediatric official positions
Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD pediatric official positions
The Task Force focusing on the use of dual energy X-ray absorptiometry (DXA) in children and adolescents with diseases that may affect the skeleton reviewed over 300 articles to establish the basis for the Official Positions. A significant number of studies used DXA-based outcome measures to assess the effects of specific interventions and charted the natural history of incremental changes in bone size and mass in specific disease states in children. However, the utility of DXA in clinical practice has not been evaluated systematically, in large part due to the lack of a workable definition for childhood osteoporosis. Thus, in combination with the Official Positions addressing the diagnosis of osteoporosis in children, and the reporting of DXA results in children, this document presents clear guidelines from which clinicians and researchers alike can work. This report delineates a set of disorders in which it is appropriate to use DXA as part of the comprehensive assessment of skeletal health in children and adolescents, and provides guidance concerning the initiation of assessment and the frequency of monitoring. Importantly, this document also highlights significant gaps in our knowledge, emphasizing areas for future research.
body Size, chronic disease, frequency, low bone mass, monitoring, osteoporosis
1094-6950
29-42
Bishop, Nick
a1a75076-bce4-486b-a24d-14988dc5f716
Braillon, Pierre
dd650dd2-8611-4114-b75b-012c93dbefaf
Burnham, Jon
2b9267ae-8e3d-462d-9134-694f3bacf6ab
Cimaz, Rolando
051df4e1-66ab-4b6f-a3d9-e102717f8029
Davies, Justin
9f18fcad-f488-4c72-ac23-c154995443a9
Fewtrell, Mary
11b8b07d-7f0f-415d-9482-f28f7f6fc57f
Hogler, Wolfgang
673de0cd-b6e1-4972-b862-e0e10110bff4
Kennedy, Kathy
e6407fd7-9dc7-471c-a17c-2e8044de8cc5
Mäkitie, Outi
bd5e8636-78a2-49f4-b71f-711bc1c15fb3
Mughal, Zulf
289613cc-a78b-4335-9221-f19419eaa32e
Shaw, Nick
a921f4ab-deb8-4d26-9518-a22126e2ef8b
Vogiatzi, Maria
41f7a7d9-afd4-460e-9cd9-efa3844c1877
Ward, Kate
2155853e-6789-49ac-bb89-bf5af6289550
Bianchi, Maria Luisa
4e324f92-c10e-42cf-b0c4-340b79013914
Bishop, Nick
a1a75076-bce4-486b-a24d-14988dc5f716
Braillon, Pierre
dd650dd2-8611-4114-b75b-012c93dbefaf
Burnham, Jon
2b9267ae-8e3d-462d-9134-694f3bacf6ab
Cimaz, Rolando
051df4e1-66ab-4b6f-a3d9-e102717f8029
Davies, Justin
9f18fcad-f488-4c72-ac23-c154995443a9
Fewtrell, Mary
11b8b07d-7f0f-415d-9482-f28f7f6fc57f
Hogler, Wolfgang
673de0cd-b6e1-4972-b862-e0e10110bff4
Kennedy, Kathy
e6407fd7-9dc7-471c-a17c-2e8044de8cc5
Mäkitie, Outi
bd5e8636-78a2-49f4-b71f-711bc1c15fb3
Mughal, Zulf
289613cc-a78b-4335-9221-f19419eaa32e
Shaw, Nick
a921f4ab-deb8-4d26-9518-a22126e2ef8b
Vogiatzi, Maria
41f7a7d9-afd4-460e-9cd9-efa3844c1877
Ward, Kate
2155853e-6789-49ac-bb89-bf5af6289550
Bianchi, Maria Luisa
4e324f92-c10e-42cf-b0c4-340b79013914

Bishop, Nick, Braillon, Pierre, Burnham, Jon, Cimaz, Rolando, Davies, Justin, Fewtrell, Mary, Hogler, Wolfgang, Kennedy, Kathy, Mäkitie, Outi, Mughal, Zulf, Shaw, Nick, Vogiatzi, Maria, Ward, Kate and Bianchi, Maria Luisa (2008) Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD pediatric official positions. Journal of Clinical Densitometry, 11 (1), 29-42. (doi:10.1016/j.jocd.2007.12.004). (PMID:18442751)

Record type: Article

Abstract

The Task Force focusing on the use of dual energy X-ray absorptiometry (DXA) in children and adolescents with diseases that may affect the skeleton reviewed over 300 articles to establish the basis for the Official Positions. A significant number of studies used DXA-based outcome measures to assess the effects of specific interventions and charted the natural history of incremental changes in bone size and mass in specific disease states in children. However, the utility of DXA in clinical practice has not been evaluated systematically, in large part due to the lack of a workable definition for childhood osteoporosis. Thus, in combination with the Official Positions addressing the diagnosis of osteoporosis in children, and the reporting of DXA results in children, this document presents clear guidelines from which clinicians and researchers alike can work. This report delineates a set of disorders in which it is appropriate to use DXA as part of the comprehensive assessment of skeletal health in children and adolescents, and provides guidance concerning the initiation of assessment and the frequency of monitoring. Importantly, this document also highlights significant gaps in our knowledge, emphasizing areas for future research.

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Published date: January 2008
Keywords: body Size, chronic disease, frequency, low bone mass, monitoring, osteoporosis
Organisations: Human Development & Health

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Local EPrints ID: 337305
URI: https://eprints.soton.ac.uk/id/eprint/337305
ISSN: 1094-6950
PURE UUID: 81c2f2fa-df47-4161-b38a-40eef80ae898

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Date deposited: 23 Apr 2012 15:26
Last modified: 18 Jul 2017 06:03

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Contributors

Author: Nick Bishop
Author: Pierre Braillon
Author: Jon Burnham
Author: Rolando Cimaz
Author: Justin Davies
Author: Mary Fewtrell
Author: Wolfgang Hogler
Author: Kathy Kennedy
Author: Outi Mäkitie
Author: Zulf Mughal
Author: Nick Shaw
Author: Maria Vogiatzi
Author: Kate Ward
Author: Maria Luisa Bianchi

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