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The first total synthesis of (+)-mucosin

Henderson, Alan R., Stec, Jozef, Owen, David R. and Whitby, Richard J. (2012) The first total synthesis of (+)-mucosin Chemical Communications, 48, (28), pp. 3409-3411. (doi:10.1039/c2cc17915f). (PMID:22358150).

Record type: Article


The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous stereocentres around the unusual bicyclo[4.3.0]nonene core.

PDF papers_In progress_Whitby_Mucosin Paper RJW + cover.pdf - Accepted Manuscript
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Published date: 10 February 2012
Organisations: Characterisation and Analytics, Organic Chemistry: Synthesis, Catalysis and Flow, Chemistry, Faculty of Natural and Environmental Sciences


Local EPrints ID: 337314
ISSN: 1359-7345
PURE UUID: 7dd8fab8-a2d9-4684-8888-4b762feb06c3
ORCID for Richard J. Whitby: ORCID iD

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Date deposited: 24 Apr 2012 09:22
Last modified: 18 Jul 2017 06:03

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