Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis
Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis
Recurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity.
519-537
Tebruegge, Marc
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Curtis, Nigel
60e08f70-7ce9-42b3-8074-d5df55131b12
July 2008
Tebruegge, Marc
2c3dff22-0b5f-48a7-bb36-ce323705f74a
Curtis, Nigel
60e08f70-7ce9-42b3-8074-d5df55131b12
Tebruegge, Marc and Curtis, Nigel
(2008)
Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis.
Clinical Microbiology Reviews, 21 (3), .
(doi:10.1128/CMR.00009-08).
(PMID:18625686)
Abstract
Recurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity.
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Published date: July 2008
Organisations:
Faculty of Medicine
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Local EPrints ID: 337541
URI: http://eprints.soton.ac.uk/id/eprint/337541
ISSN: 0893-8512
PURE UUID: f5c7454e-a47f-41ab-a9c0-11bee74f5133
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Date deposited: 27 Apr 2012 10:04
Last modified: 14 Mar 2024 10:54
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Author:
Marc Tebruegge
Author:
Nigel Curtis
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