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Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis

Tebruegge, Marc and Curtis, Nigel (2008) Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis Clinical Microbiology Reviews, 21, (3), pp. 519-537. (doi:10.1128/CMR.00009-08). (PMID:18625686).

Record type: Article


Recurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity.

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Published date: July 2008
Organisations: Faculty of Medicine


Local EPrints ID: 337541
ISSN: 0893-8512
PURE UUID: f5c7454e-a47f-41ab-a9c0-11bee74f5133

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Date deposited: 27 Apr 2012 10:04
Last modified: 18 Jul 2017 06:02

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Author: Marc Tebruegge
Author: Nigel Curtis

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