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Histological assessment of the Sydney classification of endoscopic gastritis

Khakoo, S. I., Lobo, A. J., Shepherd, N. A. and Wilkinson, S. P. (1994) Histological assessment of the Sydney classification of endoscopic gastritis Gut, 35, (9), pp. 1172-1175. (doi:10.1136/gut.35.9.1172). (PMID:7959220).

Record type: Article


To determine the significance of the endoscopic classification of gastritis proposed by a working party at the World Congress of Gastroenterology in Sydney 1990, 167 patients undergoing upper alimentary endoscopy were
prospectively assessed by comprehensive endoscopic and histological methods. Ninety eight patients had endoscopic
mucosal changes of gastritis according to the Sydney classification. Twenty six (27%) of these had histologically normal biopsy specimens. This was not statistically significantly different to the 26 (38%)
of 69 with normal endoscopies whose biopsy specimens were histologically normal (X2= 1.857, p>Ol). Forty three
(62.5%) patients with normal endoscopies had histological gastritis. No histological counterpart was found for the macroscopic appearances of the gastric mucosa said to show inflammation proposed by the Sydney classification of gastritis. These findings confirm the inappropriateness
of an endoscopic diagnosis of gastritis and it is suggested such a term should be reserved for the histological

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Published date: September 1994
Organisations: Clinical & Experimental Sciences


Local EPrints ID: 337664
ISSN: 0017-5749
PURE UUID: c8b33920-be09-483f-9825-4829623df986

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Date deposited: 30 May 2012 13:13
Last modified: 18 Jul 2017 06:01

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Author: S. I. Khakoo
Author: A. J. Lobo
Author: N. A. Shepherd
Author: S. P. Wilkinson

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