The University of Southampton
University of Southampton Institutional Repository

Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma

Johnson, David C., Corthals, Sophie L., Walker, Brian A., Ross, Fiona M., Gregory, Walter M., Dickens, Nicholas J., Lokhorst, Henk M., Goldschmidt, Hartmut, Davies, Faith E., Durie, Brian G. M., Van Ness, Brian, Child, J. Anthony, Sonneveld, Pieter and Morgan, Gareth J. (2011) Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma Journal of Clinical Oncology, 29, (7), pp. 797-804. (doi:10.1200/JCO.2010.28.0792). (PMID:21245424).

Record type: Article


Our results are consistent with the hypothesis that an individual's risk of developing a peripheral neuropathy after thalidomide treatment can be mediated by polymorphisms in genes governing repair mechanisms and inflammation in the peripheral nervous system. These findings will contribute to the development of future neuroprotective strategies with thalidomide therapy and the better use of this important compound.

Full text not available from this repository.

More information

e-pub ahead of print date: 18 January 2011
Published date: 1 March 2011
Organisations: Human Development & Health


Local EPrints ID: 337735
ISSN: 1527-7755
PURE UUID: a2abcbce-8271-4131-a4d2-8ac25c6b1c0a

Catalogue record

Date deposited: 02 May 2012 14:03
Last modified: 18 Jul 2017 06:01

Export record



Author: David C. Johnson
Author: Sophie L. Corthals
Author: Brian A. Walker
Author: Fiona M. Ross
Author: Walter M. Gregory
Author: Nicholas J. Dickens
Author: Henk M. Lokhorst
Author: Hartmut Goldschmidt
Author: Faith E. Davies
Author: Brian G. M. Durie
Author: Brian Van Ness
Author: J. Anthony Child
Author: Pieter Sonneveld
Author: Gareth J. Morgan

University divisions

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton:

ePrints Soton supports OAI 2.0 with a base URL of

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.