Plasma nitroso compounds are decreased in patients with endothelial dysfunction
Plasma nitroso compounds are decreased in patients with endothelial dysfunction
Endothelial dysfunction in patients with cardiovascular risk factors is associated with decreased levels of circulating RXNOs. Plasma RXNOs may be diagnostically useful markers of NO bioavailability and a surrogate index of endothelial function. Whether the observed decrease in concentration reflects impaired NO formation, accelerated decomposition, and/or consumption of RXNOs and whether these processes play a causal role in the pathophysiology of arteriosclerosis remain to be investigated.
573-579
Heiss, Christian
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Lauer, Thomas
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Dejam, André
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Kleinbongard, Petra
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Hamada, Sandra
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Rassaf, Tienush
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Matern, Simone
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Feelisch, Martin
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Kelm, Malte
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7 February 2006
Heiss, Christian
fd74a18a-b1d8-4b67-bf85-ea46bffa87ce
Lauer, Thomas
57e1e8b6-cfc8-40ac-a946-5ad6e3387477
Dejam, André
f3491272-d900-4d46-91ed-a684b5c14e42
Kleinbongard, Petra
ec93ff61-c3f2-4d2e-a465-59cc949315bb
Hamada, Sandra
c99a52a4-7250-4b0e-a207-4225d40b23dc
Rassaf, Tienush
a820a375-219a-4fa2-ae10-e77f4b1eb37c
Matern, Simone
7d9792a0-fbb1-4a9a-a00b-c9d00bb0404d
Feelisch, Martin
8c1b9965-8614-4e85-b2c6-458a2e17eafd
Kelm, Malte
db2bb062-32d7-4b50-9f65-8ba89ffa5f42
Heiss, Christian, Lauer, Thomas, Dejam, André, Kleinbongard, Petra, Hamada, Sandra, Rassaf, Tienush, Matern, Simone, Feelisch, Martin and Kelm, Malte
(2006)
Plasma nitroso compounds are decreased in patients with endothelial dysfunction.
Journal of the American College of Cardiology, 47 (3), .
(doi:10.1016/j.jacc.2005.06.089).
(PMID:16458138)
Abstract
Endothelial dysfunction in patients with cardiovascular risk factors is associated with decreased levels of circulating RXNOs. Plasma RXNOs may be diagnostically useful markers of NO bioavailability and a surrogate index of endothelial function. Whether the observed decrease in concentration reflects impaired NO formation, accelerated decomposition, and/or consumption of RXNOs and whether these processes play a causal role in the pathophysiology of arteriosclerosis remain to be investigated.
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Published date: 7 February 2006
Organisations:
Clinical & Experimental Sciences
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Local EPrints ID: 337834
URI: http://eprints.soton.ac.uk/id/eprint/337834
ISSN: 0735-1097
PURE UUID: fb4daf2c-b494-4317-a47b-3a998d139122
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Date deposited: 01 Jun 2012 09:11
Last modified: 15 Mar 2024 03:41
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Author:
Christian Heiss
Author:
Thomas Lauer
Author:
André Dejam
Author:
Petra Kleinbongard
Author:
Sandra Hamada
Author:
Tienush Rassaf
Author:
Simone Matern
Author:
Malte Kelm
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