Improving recruitment of older people to research through good practice
Improving recruitment of older people to research through good practice
There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49%), drop out rates (5–37%) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population
recruitment, clinical trials, efficiency, older, elderly
659-665
McMurdo, Marion E.
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Roberts, Helen
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Parker, Stuart
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Wyatt, Nikki
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May, Helen
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Goodman, Claire
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Jackson, Stephen
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Gladman, John
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O'Mahony, Sinead
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Ali, Khalid
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Dickinson, Edward
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Edison, Paul
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Dyer, Chris
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and on behalf of the Age and Ageing Specialty Group, NIHR, Comprehensive Clinical Research Network
November 2011
McMurdo, Marion E.
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Roberts, Helen
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Parker, Stuart
17ef5cb5-c646-4ea5-8197-7742cb32e271
Wyatt, Nikki
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May, Helen
1ba21e05-2054-4115-9a0c-8a3cf4c4b017
Goodman, Claire
618937cc-6275-41e9-b244-8e96b83dc675
Jackson, Stephen
ad46a012-1241-49a0-a7ba-d92094db6fc3
Gladman, John
89788999-01d4-4bd1-adb0-d96b68f2f270
O'Mahony, Sinead
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Ali, Khalid
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Dickinson, Edward
196f7e28-f246-451a-bb1d-8e8d59e80233
Edison, Paul
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Dyer, Chris
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McMurdo, Marion E., Roberts, Helen, Parker, Stuart, Wyatt, Nikki, May, Helen, Goodman, Claire, Jackson, Stephen, Gladman, John, O'Mahony, Sinead, Ali, Khalid, Dickinson, Edward, Edison, Paul and Dyer, Chris
,
and on behalf of the Age and Ageing Specialty Group, NIHR, Comprehensive Clinical Research Network
(2011)
Improving recruitment of older people to research through good practice.
Age and Ageing, 40 (6), .
(doi:10.1093/ageing/afr115).
(PMID:21911335)
Abstract
There is widespread evidence both of the exclusion of older people from clinical research, and of under-recruitment to clinical trials. This review and opinion piece provides practical advice to assist researchers both to adopt realistic, achievable recruitment rates and to increase the number of older people taking part in research. It analyses 14 consecutive recently published trials, providing the number needed to be screened to recruit one older participant (around 3:1), numbers excluded (up to 49%), drop out rates (5–37%) and whether the planned power was achieved. The value of planning and logistics are outlined, and approaches to optimising recruitment in hospital, primary care and care home settings are discussed, together with the challenges of involving older adults with mental incapacity and those from minority groups in research. The increasingly important task of engaging older members of the public and older patients in research is also discussed. Increasing the participation of older people in research will improve the generalisability of research findings and inform best practice in the clinical management of the growing older population
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e-pub ahead of print date: 11 September 2011
Published date: November 2011
Keywords:
recruitment, clinical trials, efficiency, older, elderly
Organisations:
Faculty of Health Sciences
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Local EPrints ID: 338183
URI: http://eprints.soton.ac.uk/id/eprint/338183
ISSN: 0002-0729
PURE UUID: c865d521-b60b-404e-bf8a-a7601e58cdbb
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Date deposited: 11 May 2012 10:32
Last modified: 15 Mar 2024 03:14
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Contributors
Author:
Marion E. McMurdo
Author:
Stuart Parker
Author:
Nikki Wyatt
Author:
Helen May
Author:
Claire Goodman
Author:
Stephen Jackson
Author:
John Gladman
Author:
Sinead O'Mahony
Author:
Khalid Ali
Author:
Edward Dickinson
Author:
Paul Edison
Author:
Chris Dyer
Corporate Author: and on behalf of the Age and Ageing Specialty Group, NIHR, Comprehensive Clinical Research Network
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