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The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos.

The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos.
The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos.
These data suggest that both the developmental arrest of a significant proportion of mosaic embryos on Day 4, and the cell death or reduced proliferation of aneuploid cells within an embryo may be responsible for the observed decrease of aneuploid blastomeres from compaction to the peri-implantation stage.
1916-1926
Santos, Margarida Avo
dc5e07b5-647e-49ca-9f19-a8f90eed45e7
Teklenburg, Gijs
fa31dd22-a287-4414-b255-177f5a080b03
Macklon, Nick S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Van Opstal, Diane
c8f4d301-0881-40cc-888c-5398698695b1
Schuring-Blom, G Heleen
23cfbe68-af72-4ace-ae18-085f765dd8a1
Krijtenburg, Pieter-Jaap
c0ba7cc1-1149-487c-a5c5-d0f8be71b313
de Vreeden-Elbertse, Johanna
4846d1b2-16f5-4255-8d72-4f8934a4b612
Fauser, Bart C
3d39c480-b1db-4439-af4a-49fae755ab77
Baart, Esther B
0e21ec10-6167-4264-8377-de92b26b79c7
Santos, Margarida Avo
dc5e07b5-647e-49ca-9f19-a8f90eed45e7
Teklenburg, Gijs
fa31dd22-a287-4414-b255-177f5a080b03
Macklon, Nick S.
7db1f4fc-a9f6-431f-a1f2-297bb8c9fb7e
Van Opstal, Diane
c8f4d301-0881-40cc-888c-5398698695b1
Schuring-Blom, G Heleen
23cfbe68-af72-4ace-ae18-085f765dd8a1
Krijtenburg, Pieter-Jaap
c0ba7cc1-1149-487c-a5c5-d0f8be71b313
de Vreeden-Elbertse, Johanna
4846d1b2-16f5-4255-8d72-4f8934a4b612
Fauser, Bart C
3d39c480-b1db-4439-af4a-49fae755ab77
Baart, Esther B
0e21ec10-6167-4264-8377-de92b26b79c7

Santos, Margarida Avo, Teklenburg, Gijs, Macklon, Nick S., Van Opstal, Diane, Schuring-Blom, G Heleen, Krijtenburg, Pieter-Jaap, de Vreeden-Elbertse, Johanna, Fauser, Bart C and Baart, Esther B (2010) The fate of the mosaic embryo: chromosomal constitution and development of Day 4, 5 and 8 human embryos. Human Reproduction, 25 (8), 1916-1926. (doi:10.1093/humrep/deq139). (PMID:20519247)

Record type: Article

Abstract

These data suggest that both the developmental arrest of a significant proportion of mosaic embryos on Day 4, and the cell death or reduced proliferation of aneuploid cells within an embryo may be responsible for the observed decrease of aneuploid blastomeres from compaction to the peri-implantation stage.

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Published date: August 2010
Organisations: Human Development & Health

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Local EPrints ID: 338340
URI: http://eprints.soton.ac.uk/id/eprint/338340
PURE UUID: b605f356-0c7f-4268-9bb5-e7f304f51de4

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Date deposited: 15 May 2012 08:42
Last modified: 14 Mar 2024 11:04

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Contributors

Author: Margarida Avo Santos
Author: Gijs Teklenburg
Author: Nick S. Macklon
Author: Diane Van Opstal
Author: G Heleen Schuring-Blom
Author: Pieter-Jaap Krijtenburg
Author: Johanna de Vreeden-Elbertse
Author: Bart C Fauser
Author: Esther B Baart

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