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Prevalence of reported knee pain over twelve years in a community-based cohort

Prevalence of reported knee pain over twelve years in a community-based cohort
Prevalence of reported knee pain over twelve years in a community-based cohort
Objective: To describe the temporal patterns of knee pain in a community-based cohort over 12 years.

Methods: Data on self-reported knee pain at 4 time points over 12 years were analyzed in participants from the Chingford Women's Study of osteoarthritis (OA) and osteoporosis. Pain status was defined as any pain in the preceding month and pain on most days in the preceding month. This status was used to classify participants according to pain patterns of asymptomatic, persistent, incident, or intermittent pain. Multinomial logistic regression was used to identify baseline predictors for each pain pattern.

Results: Among the 489 women with complete followup data, the median age at baseline was 52 years (interquartile range [IQR] 48-58 years), the median body mass index (BMI) was 24.39 kg/m(2) (IQR 22.46-27.20), and 11.7% of the women had a Kellgren/Lawrence radiographic OA severity grade of ?2 in at least one knee. Among subjects reporting any pain in the preceding month versus those reporting pain on most days in the preceding month, 9% versus 2% had persistent pain, 24% versus 16% had incident pain, and 29% versus 18% had intermittent pain. A higher BMI was predictive of persistent pain (odds ratio [OR] 1.14, 95% confidence interval [95% CI] 1.04-1.25) and incident pain (OR 1.10, 95% CI 1.02-1.18). The presence of radiographic knee OA was predictive of persistent pain (OR 3.70, 95% CI 1.34-10.28; P = 0.012), and reported knee injury was predictive of both persistent pain (OR 4.13, 95% CI 1.34-12.66; P = 0.013) and intermittent pain (OR 4.25, 95% CI 1.81-9.98; P = 0.001).

Conclusion: Significant variability in the temporal fluctuation of self-reported knee pain was seen in this community-based prospective study over a period of 12 years, with few women consistently reporting knee pain at each time point. Distinct baseline predictors for each pain pattern were identified and may explain the observed heterogeneity of self-reported knee pain when pain status is measured at only one time point.
0004-3591
1145-1152
Soni, A.
7a4196ff-0f6b-429e-af54-d1036e9c433b
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Hart, D.J.
00e78191-ce14-4b5f-a720-9f1bb51b2b62
Leyland, K.M.
bc5505c2-497c-4aa8-8b9b-29ee14853651
Goulston, Lyndsey M.
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Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Javaid, M.K.
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Spector, T.D.
87d1f285-3f22-4c9a-b006-d65cfda6d3e0
Arden, N.K.
23af958d-835c-4d79-be54-4bbe4c68077f
Soni, A.
7a4196ff-0f6b-429e-af54-d1036e9c433b
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Hart, D.J.
00e78191-ce14-4b5f-a720-9f1bb51b2b62
Leyland, K.M.
bc5505c2-497c-4aa8-8b9b-29ee14853651
Goulston, Lyndsey M.
a7e620bf-d0d7-422d-9872-e9c43f79bfe9
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Javaid, M.K.
51d3310b-032e-4c15-83ac-b878bce090f3
Spector, T.D.
87d1f285-3f22-4c9a-b006-d65cfda6d3e0
Arden, N.K.
23af958d-835c-4d79-be54-4bbe4c68077f

Soni, A., Kiran, A., Hart, D.J., Leyland, K.M., Goulston, Lyndsey M., Cooper, C., Javaid, M.K., Spector, T.D. and Arden, N.K. (2012) Prevalence of reported knee pain over twelve years in a community-based cohort. Arthritis & Rheumatism, 64 (4), 1145-1152. (doi:10.1002/art.33434). (PMID:22180258)

Record type: Article

Abstract

Objective: To describe the temporal patterns of knee pain in a community-based cohort over 12 years.

Methods: Data on self-reported knee pain at 4 time points over 12 years were analyzed in participants from the Chingford Women's Study of osteoarthritis (OA) and osteoporosis. Pain status was defined as any pain in the preceding month and pain on most days in the preceding month. This status was used to classify participants according to pain patterns of asymptomatic, persistent, incident, or intermittent pain. Multinomial logistic regression was used to identify baseline predictors for each pain pattern.

Results: Among the 489 women with complete followup data, the median age at baseline was 52 years (interquartile range [IQR] 48-58 years), the median body mass index (BMI) was 24.39 kg/m(2) (IQR 22.46-27.20), and 11.7% of the women had a Kellgren/Lawrence radiographic OA severity grade of ?2 in at least one knee. Among subjects reporting any pain in the preceding month versus those reporting pain on most days in the preceding month, 9% versus 2% had persistent pain, 24% versus 16% had incident pain, and 29% versus 18% had intermittent pain. A higher BMI was predictive of persistent pain (odds ratio [OR] 1.14, 95% confidence interval [95% CI] 1.04-1.25) and incident pain (OR 1.10, 95% CI 1.02-1.18). The presence of radiographic knee OA was predictive of persistent pain (OR 3.70, 95% CI 1.34-10.28; P = 0.012), and reported knee injury was predictive of both persistent pain (OR 4.13, 95% CI 1.34-12.66; P = 0.013) and intermittent pain (OR 4.25, 95% CI 1.81-9.98; P = 0.001).

Conclusion: Significant variability in the temporal fluctuation of self-reported knee pain was seen in this community-based prospective study over a period of 12 years, with few women consistently reporting knee pain at each time point. Distinct baseline predictors for each pain pattern were identified and may explain the observed heterogeneity of self-reported knee pain when pain status is measured at only one time point.

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Published date: 27 March 2012
Organisations: Faculty of Medicine, Faculty of Health Sciences

Identifiers

Local EPrints ID: 338780
URI: http://eprints.soton.ac.uk/id/eprint/338780
ISSN: 0004-3591
PURE UUID: 478df17e-34fc-4a13-8cb6-69b185ef9d3a
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

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Date deposited: 16 May 2012 09:13
Last modified: 17 Dec 2019 01:56

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Contributors

Author: A. Soni
Author: A. Kiran
Author: D.J. Hart
Author: K.M. Leyland
Author: Lyndsey M. Goulston
Author: C. Cooper ORCID iD
Author: M.K. Javaid
Author: T.D. Spector
Author: N.K. Arden

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