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Ten-year experience of home parenteral nutrition in a single centre

Ten-year experience of home parenteral nutrition in a single centre
Ten-year experience of home parenteral nutrition in a single centre
Aim: Recent data are scarce on the provision of home parenteral nutrition (HPN) in children from the UK but would help to commission intestinal failure services. Our aim was to describe 10 years of HPN experience in our centre, which serves a population of 650 000 children.

Methods: Outcome and complication data were collected retrospectively from hospital records of children receiving HPN from April 2001. Data from other centres were used to compare complications and outcomes in the provision of HPN.

Results: Nineteen children (12 females) received 10 213 days (28 years) of HPN. In this group, incidence of blood culture positive sepsis was four episodes ? 1000 days PN. Two children had early intestinal failure–associated liver disease. Of the 19, seven still receive HPN at our centre, six survived PN, three were transferred to other services while still on HPN and three died.

Conclusion: Outcome and complication data for HPN from a single UK regional paediatric centre are similar to larger centres. These data provide recent evidence of the disease burden of HPN, which are important for the commissioning of intestinal failure services.
home parenteral nutrition, intestinal failure, paediatrics, parenteral nutrition
0803-5253
524-527
Wiskin, Anthony E.
83fd2f91-d1b5-46ae-b237-8f1b61fdec29
Cole, Caroline
75887131-2248-4741-a647-b0a0bdca565f
Owens, Daniel R.
eadca0e0-5c9b-456a-b5d9-95f26060c060
Morgan, Mary
ee43f2e9-c61d-4b13-9fbf-8637c76ac850
Burge, David M.
8cb219be-d961-4da6-8d9c-ce4f54f8902c
Beattie, R. Mark
55d81c7b-08c9-4f42-b6d3-245869badb71
Wiskin, Anthony E.
83fd2f91-d1b5-46ae-b237-8f1b61fdec29
Cole, Caroline
75887131-2248-4741-a647-b0a0bdca565f
Owens, Daniel R.
eadca0e0-5c9b-456a-b5d9-95f26060c060
Morgan, Mary
ee43f2e9-c61d-4b13-9fbf-8637c76ac850
Burge, David M.
8cb219be-d961-4da6-8d9c-ce4f54f8902c
Beattie, R. Mark
55d81c7b-08c9-4f42-b6d3-245869badb71

Wiskin, Anthony E., Cole, Caroline, Owens, Daniel R., Morgan, Mary, Burge, David M. and Beattie, R. Mark (2012) Ten-year experience of home parenteral nutrition in a single centre. Acta Paediatrica, 101 (5), 524-527. (doi:10.1111/j.1651-2227.2012.02594.x). (PMID:22233229)

Record type: Article

Abstract

Aim: Recent data are scarce on the provision of home parenteral nutrition (HPN) in children from the UK but would help to commission intestinal failure services. Our aim was to describe 10 years of HPN experience in our centre, which serves a population of 650 000 children.

Methods: Outcome and complication data were collected retrospectively from hospital records of children receiving HPN from April 2001. Data from other centres were used to compare complications and outcomes in the provision of HPN.

Results: Nineteen children (12 females) received 10 213 days (28 years) of HPN. In this group, incidence of blood culture positive sepsis was four episodes ? 1000 days PN. Two children had early intestinal failure–associated liver disease. Of the 19, seven still receive HPN at our centre, six survived PN, three were transferred to other services while still on HPN and three died.

Conclusion: Outcome and complication data for HPN from a single UK regional paediatric centre are similar to larger centres. These data provide recent evidence of the disease burden of HPN, which are important for the commissioning of intestinal failure services.

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More information

e-pub ahead of print date: 27 January 2012
Published date: May 2012
Keywords: home parenteral nutrition, intestinal failure, paediatrics, parenteral nutrition
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 338920
URI: http://eprints.soton.ac.uk/id/eprint/338920
ISSN: 0803-5253
PURE UUID: 4d331546-e25e-4106-940c-05e780a1abb1

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Date deposited: 18 May 2012 13:24
Last modified: 14 Mar 2024 11:07

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Contributors

Author: Anthony E. Wiskin
Author: Caroline Cole
Author: Daniel R. Owens
Author: Mary Morgan
Author: David M. Burge
Author: R. Mark Beattie

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