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Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
Here we present a novel surface modification method based on the sequential layer-by-layer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. The coatings are long-term stable and allow for the generation of monodisperse oil-in-water microdroplets even several months after the channel surface treatment. Due to the robustness of the polyelectrolyte multilayers ultra-high flow rates can be applied, making high-throughput droplet formation in the jetting mode possible. Furthermore, we successfully used our method to selectively modify the surface properties in certain areas of assembled microchannels. The resulting partially hydrophilic, partially hydrophobic microfluidic devices allow for the production of monodisperse water-in-oil-in-water double emulsions.



1473-0197
1814-1819
Bauer, Wolfgang-Andreas C.
0cfaa8bc-3cf7-449b-b6d4-13bdcfd6f356
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Abell, Chris
9b071a5d-04c5-464e-8d19-e37e41d1a046
Huck, Wilhelm T. S.
1495471b-acd7-40d2-a32e-99b98d36b936
Bauer, Wolfgang-Andreas C.
0cfaa8bc-3cf7-449b-b6d4-13bdcfd6f356
Fischlechner, Martin
b3930129-0775-4c05-81c7-475934df97ee
Abell, Chris
9b071a5d-04c5-464e-8d19-e37e41d1a046
Huck, Wilhelm T. S.
1495471b-acd7-40d2-a32e-99b98d36b936

Bauer, Wolfgang-Andreas C., Fischlechner, Martin, Abell, Chris and Huck, Wilhelm T. S. (2010) Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions. Lab on a Chip, 10 (14), 1814-1819. (doi:10.1039/c004046k).

Record type: Article

Abstract

Here we present a novel surface modification method based on the sequential layer-by-layer deposition of polyelectrolytes yielding hydrophilic microchannels in PDMS-based microfluidic devices. The coatings are long-term stable and allow for the generation of monodisperse oil-in-water microdroplets even several months after the channel surface treatment. Due to the robustness of the polyelectrolyte multilayers ultra-high flow rates can be applied, making high-throughput droplet formation in the jetting mode possible. Furthermore, we successfully used our method to selectively modify the surface properties in certain areas of assembled microchannels. The resulting partially hydrophilic, partially hydrophobic microfluidic devices allow for the production of monodisperse water-in-oil-in-water double emulsions.



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Published date: 5 May 2010
Organisations: Chemistry

Identifiers

Local EPrints ID: 340194
URI: https://eprints.soton.ac.uk/id/eprint/340194
ISSN: 1473-0197
PURE UUID: 40a5ec58-ca02-4b4a-9e42-845b38649912

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Date deposited: 14 Jun 2012 14:20
Last modified: 30 Jul 2019 18:56

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