The University of Southampton
University of Southampton Institutional Repository
Warning ePrints Soton is experiencing an issue with some file downloads not being available. We are working hard to fix this. Please bear with us.

The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database

The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database
The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database
Objective: To estimate the lifetime risk of undergoing primary total hip (THR) or knee (TKR) replacement in the UK.

Method: A Population-based cohort study of 25,845 patients who had undergone a THR and 23,260 patients who had undergone a TKR between 1991 and 2006, using data from the UK General Practice Research Database.

Results: The estimated mortality-adjusted lifetime risk of THR at age 50 for the year 2005 was 11.6% (95% CI: 11.1, 12.1) for women and 7.1% (95% CI: 6.7, 7.5) for men. For TKR the risks were 10.8% (95% CI:10.3, 11.3) for women and 8.1% (95% CI: 7.6, 8.5) for men. Between 1991 and 2006, the lifetime risk of THR at age 50 rose from 4.0% (95% CI: 3.5, 4.4) to 11.1% (95% CI: 10.6, 11.6) for women and for men from 2.2%(95% CI: 1.8, 2.5) to 6.6% (95% CI: 6.2, 7.0). Over the same period, for TKR the risk for women increased
from 2.9% (95% CI: 2.6, 3.3) to 10.6% (95% CI: 10.1, 11.1) and for men from 1.8% (95% CI: 1.5, 2.2) to 7.7%(95% CI: 7.3, 8.2).

Conclusion: The lifetime risk of undergoing THR or TKR is estimated to be substantially less than the risk of developing symptomatic hip or knee osteoarthritis. For the knee, the difference between these risk estimates is particularly wide. The reasons for the size of these differences are not clear, and further work is needed to quantify the extent of latent demand for these cost-effective and established interventions among the population with symptomatic osteoarthritis of the hip or knee.
1063-4584
519-524
Culliford, D. J.
25511573-74d3-422a-b0ee-dfe60f80df87
Maskell, J.
7edffaec-77e7-49e6-9bd8-d1a98af01185
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Judge, A.
c6a83964-1d7c-4aa8-b2bf-9c264d1e487d
Javaid, M. K.
8841650b-9deb-4d23-933b-6be97763ba65
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Arden, N. K.
23af958d-835c-4d79-be54-4bbe4c68077f
Culliford, D. J.
25511573-74d3-422a-b0ee-dfe60f80df87
Maskell, J.
7edffaec-77e7-49e6-9bd8-d1a98af01185
Kiran, A.
5c4f2210-4951-4226-a44b-e6ecfb9c5c71
Judge, A.
c6a83964-1d7c-4aa8-b2bf-9c264d1e487d
Javaid, M. K.
8841650b-9deb-4d23-933b-6be97763ba65
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Arden, N. K.
23af958d-835c-4d79-be54-4bbe4c68077f

Culliford, D. J., Maskell, J., Kiran, A., Judge, A., Javaid, M. K., Cooper, C. and Arden, N. K. (2012) The lifetime risk of total hip and knee arthroplasty: results from the UK general practice research database. Osteoarthritis and Cartilage, 20 (6), 519-524. (doi:10.1016/j.joca.2012.02.636). (PMID:22395038)

Record type: Article

Abstract

Objective: To estimate the lifetime risk of undergoing primary total hip (THR) or knee (TKR) replacement in the UK.

Method: A Population-based cohort study of 25,845 patients who had undergone a THR and 23,260 patients who had undergone a TKR between 1991 and 2006, using data from the UK General Practice Research Database.

Results: The estimated mortality-adjusted lifetime risk of THR at age 50 for the year 2005 was 11.6% (95% CI: 11.1, 12.1) for women and 7.1% (95% CI: 6.7, 7.5) for men. For TKR the risks were 10.8% (95% CI:10.3, 11.3) for women and 8.1% (95% CI: 7.6, 8.5) for men. Between 1991 and 2006, the lifetime risk of THR at age 50 rose from 4.0% (95% CI: 3.5, 4.4) to 11.1% (95% CI: 10.6, 11.6) for women and for men from 2.2%(95% CI: 1.8, 2.5) to 6.6% (95% CI: 6.2, 7.0). Over the same period, for TKR the risk for women increased
from 2.9% (95% CI: 2.6, 3.3) to 10.6% (95% CI: 10.1, 11.1) and for men from 1.8% (95% CI: 1.5, 2.2) to 7.7%(95% CI: 7.3, 8.2).

Conclusion: The lifetime risk of undergoing THR or TKR is estimated to be substantially less than the risk of developing symptomatic hip or knee osteoarthritis. For the knee, the difference between these risk estimates is particularly wide. The reasons for the size of these differences are not clear, and further work is needed to quantify the extent of latent demand for these cost-effective and established interventions among the population with symptomatic osteoarthritis of the hip or knee.

This record has no associated files available for download.

More information

Published date: June 2012
Organisations: Faculty of Health Sciences, Primary Care & Population Sciences

Identifiers

Local EPrints ID: 340439
URI: http://eprints.soton.ac.uk/id/eprint/340439
ISSN: 1063-4584
PURE UUID: 708b6667-acf3-4859-a3a0-73af05d6fb9b
ORCID for D. J. Culliford: ORCID iD orcid.org/0000-0003-1663-0253
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 21 Jun 2012 14:48
Last modified: 09 Nov 2021 03:10

Export record

Altmetrics

Contributors

Author: D. J. Culliford ORCID iD
Author: J. Maskell
Author: A. Kiran
Author: A. Judge
Author: M. K. Javaid
Author: C. Cooper ORCID iD
Author: N. K. Arden

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×