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A statistical validation of the Brief ICF Core Set for osteoarthritis based on a large international sample of patients with osteoarthritis

A statistical validation of the Brief ICF Core Set for osteoarthritis based on a large international sample of patients with osteoarthritis
A statistical validation of the Brief ICF Core Set for osteoarthritis based on a large international sample of patients with osteoarthritis
Objective: With the International Classification of Functioning, Disability and Health (ICF), the impact of health conditions on functioning and disability can be described. A Comprehensive and Brief ICF Core Set for osteoarthritis (OA) were developed. Our specific aims were to validate the Brief ICF Core Set for OA using a novel approach, i.e. to identify ICF categories that best explain patients' functioning, and to propose a statistically-validated version.

Methods: Psychometric study using Group Lasso regression on data from a convenience sample of 879 OA patients from 20 countries. The subscale on general health of the SF-36 was used as dependent variable and all ICF categories of the Comprehensive ICF Core Set for OA and some socio-demographics and disease-specific characteristics as independent variables. The most relevant ICF categories were identified as those showing a significant effect based on the pointwise 90% confidence intervals resulting from 1000 bootstrap trials.

Results: The set of ICF categories that best explains patients' functioning consists of four body functions, two body structures, two activities and participation and three environmental factors. Twelve of the original 13 Brief ICF Core Set categories were confirmed, and three additional ICF categories were identified.

Conclusion: Our findings reassure the validity of the Brief ICF Core Set for OA. The statistically validated Core Set with the additional statistically-derived ICF categories will likely perform better with regard to discrimination and sensitivity to change in studies and trials, and should be further explored in the future.
0004-3591
177-186
Oberhauser, Cornelia
6faa2a46-71f5-439d-be9e-ba6d53b089cc
Escorpizo, Reuben
7c45c932-c7e1-4a15-b80e-376eebcfba48
Boonen, Annelies
c32bd0a4-48b2-45f9-9ab3-5ff0074b7f32
Stucki, Gerold
0534525c-103b-45be-b0a5-061d8867ef0d
Cieza, Alarcos
a0df25c5-ee2c-4580-82b3-d0a75591580e
Oberhauser, Cornelia
6faa2a46-71f5-439d-be9e-ba6d53b089cc
Escorpizo, Reuben
7c45c932-c7e1-4a15-b80e-376eebcfba48
Boonen, Annelies
c32bd0a4-48b2-45f9-9ab3-5ff0074b7f32
Stucki, Gerold
0534525c-103b-45be-b0a5-061d8867ef0d
Cieza, Alarcos
a0df25c5-ee2c-4580-82b3-d0a75591580e

Oberhauser, Cornelia, Escorpizo, Reuben, Boonen, Annelies, Stucki, Gerold and Cieza, Alarcos (2013) A statistical validation of the Brief ICF Core Set for osteoarthritis based on a large international sample of patients with osteoarthritis. Arthritis & Rheumatism, 65 (2), 177-186. (doi:10.1002/acr.21775). (PMID:22744953)

Record type: Article

Abstract

Objective: With the International Classification of Functioning, Disability and Health (ICF), the impact of health conditions on functioning and disability can be described. A Comprehensive and Brief ICF Core Set for osteoarthritis (OA) were developed. Our specific aims were to validate the Brief ICF Core Set for OA using a novel approach, i.e. to identify ICF categories that best explain patients' functioning, and to propose a statistically-validated version.

Methods: Psychometric study using Group Lasso regression on data from a convenience sample of 879 OA patients from 20 countries. The subscale on general health of the SF-36 was used as dependent variable and all ICF categories of the Comprehensive ICF Core Set for OA and some socio-demographics and disease-specific characteristics as independent variables. The most relevant ICF categories were identified as those showing a significant effect based on the pointwise 90% confidence intervals resulting from 1000 bootstrap trials.

Results: The set of ICF categories that best explains patients' functioning consists of four body functions, two body structures, two activities and participation and three environmental factors. Twelve of the original 13 Brief ICF Core Set categories were confirmed, and three additional ICF categories were identified.

Conclusion: Our findings reassure the validity of the Brief ICF Core Set for OA. The statistically validated Core Set with the additional statistically-derived ICF categories will likely perform better with regard to discrimination and sensitivity to change in studies and trials, and should be further explored in the future.

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More information

e-pub ahead of print date: 30 June 2012
Published date: February 2013
Organisations: Psychology

Identifiers

Local EPrints ID: 340817
URI: http://eprints.soton.ac.uk/id/eprint/340817
ISSN: 0004-3591
PURE UUID: aca827f8-5207-4ae1-8bbf-04f33d468706

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Date deposited: 03 Jul 2012 12:32
Last modified: 14 Mar 2024 11:30

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Contributors

Author: Cornelia Oberhauser
Author: Reuben Escorpizo
Author: Annelies Boonen
Author: Gerold Stucki
Author: Alarcos Cieza

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